Associations between children’s family environment, spontaneous brain oscillations, and emotional and behavioral problems

The family environment in childhood has a strong effect on mental health outcomes throughout life. This effect is thought to depend at least in part on modifications of neurodevelopment trajectories. In this exploratory study, we sought to investigate whether a feasible resting-state fMRI metric of...

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Bibliographic Details
Published in:European child & adolescent psychiatry 2019-06, Vol.28 (6), p.835-845
Main Authors: Sato, João Ricardo, Biazoli, Claudinei Eduardo, Salum, Giovanni Abrahão, Gadelha, Ary, Crossley, Nicolas, Vieira, Gilson, Zugman, André, Picon, Felipe Almeida, Pan, Pedro Mario, Hoexter, Marcelo Queiroz, Amaro, Edson, Anés, Mauricio, Moura, Luciana Monteiro, Del’Aquilla, Marco Antonio Gomes, Mcguire, Philip, Rohde, Luis Augusto, Miguel, Euripedes Constantino, Bressan, Rodrigo Affonseca, Jackowski, Andrea Parolin
Format: Article
Language:English
Subjects:
Adolescents
Behavior problems
Brain
Brain mapping
Child & adolescent psychiatry
Child and Adolescent Psychiatry
Childhood
Children
Coherence
Cortex
Cortex (temporal)
Emotional behavior
Emotional disturbances
Functional magnetic resonance imaging
Health status
Home environment
Medicine
Medicine & Public Health
Mental disorders
Mental health
Neuroimaging
Original Contribution
Oscillations
Psychiatry
Resting
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Summary:The family environment in childhood has a strong effect on mental health outcomes throughout life. This effect is thought to depend at least in part on modifications of neurodevelopment trajectories. In this exploratory study, we sought to investigate whether a feasible resting-state fMRI metric of local spontaneous oscillatory neural activity, the fractional amplitude of low-frequency fluctuations (fALFF), is associated with the levels of children’s family coherence and conflict. Moreover, we sought to further explore whether spontaneous activity in the brain areas influenced by family environment would also be associated with a mental health outcome, namely the incidence of behavioral and emotional problems. Resting-state fMRI data from 655 children and adolescents (6–15 years old) were examined. The quality of the family environment was found to be positively correlated with fALFF in the left temporal pole and negatively correlated with fALFF in the right orbitofrontal cortex. Remarkably, increased fALFF in the temporal pole was associated with a lower incidence of behavioral and emotional problems, whereas increased fALFF in the orbitofrontal cortex was correlated with a higher incidence.
ISSN:1018-8827
1435-165X
DOI:10.1007/s00787-018-1240-y