Exercise-Induced Anaphylaxis: Literature Review and Recent Updates

Purpose of Review This paper will review the pathophysiology, diagnosis, and treatment of exercise-induced anaphylaxis and food-dependent, exercise-induced anaphylaxis with an emphasis on novel studies published in the past several years. Recent Findings Exercise-induced anaphylaxis (EIAn) is a clin...

Full description

Saved in:
Bibliographic Details
Published in:Current allergy and asthma reports 2018-12, Vol.18 (12), p.72-8, Article 72
Main Author: Giannetti, Matthew P.
Format: Article
Language:English
Subjects:
Allergology
Anaphylaxis
Anaphylaxis - diagnosis
Anaphylaxis - etiology
Anaphylaxis - immunology
Anaphylaxis - therapy
Anaphylaxis and Drug Allergy (DA Khan and M Castells
Animals
Exercise
Food allergies
Food Hypersensitivity - complications
Food Hypersensitivity - diagnosis
Food Hypersensitivity - immunology
Food Hypersensitivity - therapy
Humans
Medicine
Medicine & Public Health
Section Editors
Topical Collection on Anaphylaxis and Drug Allergy
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose of Review This paper will review the pathophysiology, diagnosis, and treatment of exercise-induced anaphylaxis and food-dependent, exercise-induced anaphylaxis with an emphasis on novel studies published in the past several years. Recent Findings Exercise-induced anaphylaxis (EIAn) is a clinical syndrome characterized by anaphylaxis during or shortly after physical exertion. The syndrome is broadly grouped into two categories: exercise-induced anaphylaxis and food-dependent, exercise-induced anaphylaxis (FDEIAn). Recent literature indicates that FDEIAn is a primary IgE-mediated food allergy which is augmented by several cofactors. Cofactors such as exercise, NSAIDs, and alcohol increase intestinal permeability and allow increased antigen uptake, thereby causing symptoms. The pathophysiology of EIAn is still under investigation. Summary EIAn and FDEIAn are rare clinical syndromes characterized by symptoms during or shortly after exercise. Despite recent advances in the understanding of EIAn and FDEIAn, the pathophysiology of both conditions is not fully understood.
ISSN:1529-7322
1534-6315
DOI:10.1007/s11882-018-0830-6