A Dilution Model for Embryonic Scaling

A Dilution Model for Embryonic Scaling

A recent study in Nature Cell Biology (Almuedo-Castillo et al., 2018) describes a mechanism for tissue scaling in zebrafish embryos. The authors show that a fixed relative amount of the diffusible Nodal inhibitor Lefty produces an extended gradient in larger embryos, ensuring proportionally scaled g...

Full description

Saved in:
Bibliographic Details
Published in:Developmental cell 2018-09, Vol.46 (5), p.529-530
Main Author: Marshall, Wallace F.
Format: Article
Language:eng
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A recent study in Nature Cell Biology (Almuedo-Castillo et al., 2018) describes a mechanism for tissue scaling in zebrafish embryos. The authors show that a fixed relative amount of the diffusible Nodal inhibitor Lefty produces an extended gradient in larger embryos, ensuring proportionally scaled germ layers, irrespective of embryo size. A recent study in Nature Cell Biology (Almuedo-Castillo et al., 2018) describes a mechanism for tissue scaling in zebrafish embryos. The authors show that a fixed relative amount of the diffusible Nodal inhibitor Lefty produces an extended gradient in larger embryos, ensuring proportionally scaled germ layers, irrespective of embryo size.
ISSN:1534-5807
1878-1551