Locally advanced cervical cancer complicating pregnancy: A case of competing risks from the Catholic University of the Sacred Heart in Rome

A case of stage IB2 cervical cancer at 27 weeks of pregnancy, treated with neoadjuvant chemotherapy followed by radical Cesarean hysterectomy with full pelvic and infra-mesenteric lymphadenectomy, and adjuvant chemo-radiation is described. While she remains without disease, her baby was diagnosed wi...

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Bibliographic Details
Published in:Gynecologic oncology 2018-09, Vol.150 (3), p.398-405
Main Authors: De Vincenzo, R., Tortorella, L., Ricci, C., Cavaliere, A.F., Zannoni, G.F., Cefalo, M.G., Scambia, G., Fagotti, A.
Format: Article
Language:English
Subjects:
Cervical cancer
Neoadjuvant chemotherapy
Obstetric outcome
Pregnancy
Radical hysterectomy
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Summary:A case of stage IB2 cervical cancer at 27 weeks of pregnancy, treated with neoadjuvant chemotherapy followed by radical Cesarean hysterectomy with full pelvic and infra-mesenteric lymphadenectomy, and adjuvant chemo-radiation is described. While she remains without disease, her baby was diagnosed with acute myelogenous leukemia. We highlight the pre-operative work-up, treatment options, safety, feasibility, and outcomes for the mother and her fetus.
ISSN:0090-8258
1095-6859
DOI:10.1016/j.ygyno.2018.06.028