Short‐ and long‐term outcomes of middle hepatic vein–oriented hepatectomy for advanced perihilar cholangiocarcinoma

Background This study aimed to compare clinical outcomes of the middle hepatic vein (MHV)‐oriented versus conventional hemihepatectomy for perihilar cholangiocarcinoma (PHC). Methods From 2008 to 2017, medical records of patients undergoing hemihepatectomy with caudate lobectomy for advanced PHC wer...

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Published in:Journal of surgical oncology 2018-09, Vol.118 (3), p.446-454
Main Authors: Ji, Gu‐Wei, Zhang, Yao‐Dong, Wang, Ke, Zhang, Hui, Shao, Zi‐Cheng, Jiang, Wang‐Jie, Li, Xiang‐Cheng, Wang, Xue‐Hao
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Bile Duct Neoplasms - pathology
Bile Duct Neoplasms - surgery
Cancer surgery
Female
Follow-Up Studies
hemihepatectomy
Hepatectomy - mortality
Hepatic Veins - pathology
Hepatic Veins - surgery
Humans
Klatskin Tumor - pathology
Klatskin Tumor - surgery
Male
Middle Aged
middle hepatic vein (MHV)
Morbidity
perihilar cholangiocarcinoma (PHC)
Retrospective Studies
survival
Survival Rate
Treatment Outcome
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Summary:Background This study aimed to compare clinical outcomes of the middle hepatic vein (MHV)‐oriented versus conventional hemihepatectomy for perihilar cholangiocarcinoma (PHC). Methods From 2008 to 2017, medical records of patients undergoing hemihepatectomy with caudate lobectomy for advanced PHC were reviewed retrospectively. MHV‐oriented hepatectomy was defined as full exposure of the MHV on the dissection plane. Predictors of morbidity and survival were identified. Results A total of 125 patients were enrolled. MHV‐oriented and conventional hepatectomies were performed in 44 and 81 patients, respectively. The curative resection rate, blood loss, transfusion, and survival were comparable between two groups; however, severe morbidity rate was significantly lower in the MHV‐oriented group (9.1% vs 38.3%, P 
ISSN:0022-4790
1096-9098
DOI:10.1002/jso.25181