Natural History of Cervical Degenerative Spondylolisthesis

STUDY DESIGN.Retrospective observational and case-control study. OBJECTIVE.To determine the risk factors for progression of degenerative listhesis by comparing patients with and without progression at greater than 5-year follow-up. SUMMARY OF BACKGROUND DATA.The previous study with 2- to 7-year foll...

Full description

Saved in:
Bibliographic Details
Published in:Spine (Philadelphia, Pa. 1976) Pa. 1976), 2019-01, Vol.44 (1), p.E7-E12
Main Authors: Park, Moon Soo, Moon, Seong-Hwan, Oh, Jae Keun, Lee, Ho Won, Riew, K Daniel
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Case-Control Studies
Cervical Vertebrae - diagnostic imaging
Cervical Vertebrae - surgery
Disease Progression
Female
Follow-Up Studies
Humans
Male
Middle Aged
Retrospective Studies
Spinal Cord Diseases - diagnostic imaging
Spinal Cord Diseases - surgery
Spondylolisthesis - diagnostic imaging
Spondylolisthesis - surgery
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:STUDY DESIGN.Retrospective observational and case-control study. OBJECTIVE.To determine the risk factors for progression of degenerative listhesis by comparing patients with and without progression at greater than 5-year follow-up. SUMMARY OF BACKGROUND DATA.The previous study with 2- to 7-year follow-up showed that degenerative spondylolisthesis of the cervical spine did not progress. Longer-term follow-up may reveal that these patients actually do progress over time. METHODS.We identified 218 patients with greater than 5-year follow-up without surgery. They were categorized as either having or not having cervical spondylolisthesis. We defined spondylolisthesis as the presence of greater than 2 mm of translation in standing neutral lateral radiographs of the cervical spine at the initial evaluation. The control group at baseline was those without spondylolisthesis. Progression of translation was defined as greater than 2 mm of additional translation on the final standing neutral radiograph. RESULTS.The mean follow-up duration was 6.4 ± 1.0 years (range5–9.4 yr). Progression of translation was found in 20 patients (9.2%), including 4 patients in the spondylolisthesis group and 16 patients in the control group. Progression of translation was not related to the presence of spondylolisthesis or the severity of translation at the initial evaluation, but was more common in the elderly and in the patients with anterior translation than those with posterior translation at the initial evaluation. In addition, progression of spondylolisthesis was not correlated with any change of symptoms. CONCLUSION.Progression of cervical spondylolisthesis is not related to the presence of spondylolisthesis at baseline.Level of Evidence4
ISSN:0362-2436
1528-1159
DOI:10.1097/BRS.0000000000002764