Transcatheter arterial embolisation for acute lower gastrointestinal haemorrhage: a single-centre study

Objective To investigate the safety and efficacy of transcatheter arterial embolisation (TAE) in the management of lower gastrointestinal bleeding (LGIB) and to identify predictors of clinical outcomes. Methods Between December 2005 and April 2017, 274 patients underwent diagnostic angiography for s...

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Bibliographic Details
Published in:European radiology 2019, Vol.29 (1), p.57-67
Main Authors: Kwon, Joon Ho, Kim, Man-Deuk, Han, Kichang, Choi, Woosun, Kim, Yong Seek, Lee, Junhyung, Kim, Gyoung Min, Won, Jong Yun, Lee, Do Yun
Format: Article
Language:English
Subjects:
Acute Disease
Adolescent
Adult
Aged
Aged, 80 and over
Angiography
Bleeding
Catheterization, Peripheral - methods
Clinical outcomes
Colon
Complications
Diagnostic Radiology
Diagnostic systems
Embolization, Therapeutic - methods
Female
Gastrointestinal Hemorrhage - diagnosis
Gastrointestinal Hemorrhage - therapy
Gastrointestinal tract
Hemorrhage
Humans
Identification methods
Imaging
Internal Medicine
Interventional Radiology
Male
Medicine
Medicine & Public Health
Middle Aged
Mortality
Neuroradiology
Patients
Radiology
Rectum
Regression analysis
Retrospective Studies
Signs and symptoms
Small intestine
Success
Treatment Outcome
Ultrasound
Vascular-Interventional
Young Adult
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Summary:Objective To investigate the safety and efficacy of transcatheter arterial embolisation (TAE) in the management of lower gastrointestinal bleeding (LGIB) and to identify predictors of clinical outcomes. Methods Between December 2005 and April 2017, 274 patients underwent diagnostic angiography for signs and symptoms of LGIB; 134 patients with positive angiographic findings were retrospectively analysed. The technical success of TAE and clinical outcomes, including recurrent bleeding, major complications, and in-hospital mortality were evaluated. The associations of various clinical and technical factors with clinical outcomes were analysed. Predictors for clinical outcomes were evaluated using univariate and multivariate logistic regression analyses. Results A total of 134 patients (mean age, 59.7 years; range, 14–82 years) underwent TAE for LGIB. The bleeding foci were in the small bowel in 74 patients (55.2%), colon in 35 (26.1%), and rectum in 25 (18.7%). Technical success was achieved in 127 patients (94.8%). The clinical success rate was 63% (80/127). The rates of recurrent bleeding, major complications, and in-hospital mortality were 27.9% (31/111), 18.5% (23/124), and 23.6% (33/127), respectively. Superselective embolisation and the use of N -butyl cyanoacrylate (NBCA) were significant prognostic factors associated with reduced recurrent bleeding (OR, 0.258; p = 0.004 for superselective embolisation, OR, 0.313; p = 0.01 for NBCA) and fewer major complications (OR, 0.087; p ˂ 0.001 for superselective embolisation, OR, 0.272; p = 0.007 for NBCA). Conclusions TAE is an effective treatment modality for LGIB. Superselective embolisation is essential to reduce recurrent bleeding and avoid major complications. NBCA appears to be a preferred embolic agent. Key Points • Transcatheter arterial Embolisation (TAE) is a safe and effective treatment for lower gastrointestinal tract haemorrhage. • Superselective embolisation is essential to improve outcomes. • N-butyl cyanoacrylate (NBCA) appears to be a preferred embolic agent with better clinical outcomes.
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-018-5587-8