Unilateral or bilateral punctate hippocampal hyperintensities on DW-MRI: seizures, amnesia, or both?

The presence of small hippocampal hyperintense lesions on diffusion-weighted (DW) MRI can respond to different etiologies and represents a challenge where clinical judgment is imperative, since therapeutic approach may be quite different. We here report three patients with similar neuroradiological...

Full description

Saved in:
Bibliographic Details
Published in:Neurological sciences 2018-09, Vol.39 (9), p.1647-1649
Main Authors: Bocos-Portillo, Jone, Escalza-Cortina, Inés, Gómez-Beldarrain, Marian, Rodriguez-Sainz, Aida, Garcia-Monco, Juan Carlos
Format: Article
Language:English
Subjects:
Aged
Amnesia
Amnesia - complications
Amnesia - diagnostic imaging
Amnesia - drug therapy
Brief Communication
Convulsions & seizures
Diagnosis, Differential
Diffusion Magnetic Resonance Imaging
Female
Hippocampus
Hippocampus - diagnostic imaging
Humans
Magnetic resonance imaging
Male
Medicine
Medicine & Public Health
Middle Aged
Neurology
Neuroradiology
Neurosciences
Neurosurgery
Psychiatry
Seizures
Seizures - complications
Seizures - diagnostic imaging
Seizures - drug therapy
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The presence of small hippocampal hyperintense lesions on diffusion-weighted (DW) MRI can respond to different etiologies and represents a challenge where clinical judgment is imperative, since therapeutic approach may be quite different. We here report three patients with similar neuroradiological findings, i.e., hyperintense punctate hippocampal lesions on diffusion-weighted MRI sequences, yet of different origin. The first one presented with isolated amnesia (transient global amnesia), the second one with amnesia and seizures, and the third one with seizures. Thus, hippocampal punctate lesions appear after transient global amnesia, but the same pattern may be present after seizures, either focal-onset or generalized seizures. This peculiar radiological MRI pattern could indicate a pathogenic link between transient global amnesia (TGA) and seizures which should be further studied.
ISSN:1590-1874
1590-3478
DOI:10.1007/s10072-018-3461-8