EBUS-TBNA is Sufficient for Successful Diagnosis of Silicosis with Mediastinal Lymphadenopathy

Background Silicosis is an occupational lung disease resulting from inhalation of respirable crystalline silica. Recently, an international silicosis epidemic has been noted among artificial stone workers. Objective Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is curr...

Full description

Saved in:
Bibliographic Details
Published in:Lung 2018-08, Vol.196 (4), p.441-445
Main Authors: Shitrit, David, Adir, Yochai, Avriel, Avital, King, Daniel, Epstein Shochet, Gali, Guber, Alexander, Schnaer, Sonia, Kassirer, Michael, Blanc, Paul D., Abramovich, Amir
Format: Article
Language:English
Subjects:
Adult
Aged
Artificial stone
Bronchoscopy
Care and treatment
Complications
Diagnosis
Diagnostic systems
Dust
Endoscopic Ultrasound-Guided Fine Needle Aspiration
Epidemics
Humans
Inhalation
Interventional Bronchoscopy
Israel
Lung - pathology
Lung - surgery
Lung diseases
Lymph Nodes - pathology
Lymph Nodes - surgery
Lymphadenopathy
Lymphadenopathy - pathology
Lymphadenopathy - surgery
Male
Mediastinum
Medical diagnosis
Medicine
Medicine & Public Health
Middle Aged
Occupational diseases
Patients
Pneumology/Respiratory System
Polarized light
Predictive Value of Tests
Respiration
Retrospective Studies
Silica
Silicon dioxide
Silicosis
Silicosis - pathology
Silicosis - surgery
Surgery
Thoracic Surgery, Video-Assisted
Ultrasound
Ultrasound imaging
Workers
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Silicosis is an occupational lung disease resulting from inhalation of respirable crystalline silica. Recently, an international silicosis epidemic has been noted among artificial stone workers. Objective Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is currently used for patients with unexplained lymphadenopathy. Since silicosis may present with prominent lymphadenopathy, the diagnostic yield of EBUS-TBNA in diagnosing silicosis was evaluated. Methods Twenty-eight patients with suspected silicosis referred for outpatient evaluation in three large tertiary hospitals were evaluated. Patients with mediastinal lymphadenopathy underwent EBUS-TBNA, while others underwent TBB and/or video-assisted thoracoscopic surgery (VATS). Results Eleven patients with mediastinal lymphadenopathy (39%) were evaluated using EBUS-TBNA. The diagnosis was accurate in all cases, demonstrating silica particles under polarized light, with no complications. Among the remaining patients, TBB was only 76% diagnostic, therefore requiring VATS. Conclusions EBUS-TBNA is a useful and sufficient tool to diagnose silicosis in patients with mediastinal lymphadenopathy along compatible exposure histories.
ISSN:0341-2040
1432-1750
DOI:10.1007/s00408-018-0129-3