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Anti-Muellerian hormone-based approach to controlled ovarian stimulation for assisted conception
BACKGROUND Individualization of controlled ovarian stimulation (COS) for assisted conception is complicated by variable ovarian response to follicle stimulating hormone. We hypothesized that anti-Muellerian hormone (AMH), a predictor of oocyte yield, may facilitate treatment strategies for women und...
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Published in: | Human reproduction (Oxford) 2009-04, Vol.24 (4), p.867-875 |
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Main Authors: | , , , , , , , , |
Format: | Article |
Language: | English |
Online Access: | Get full text |
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Summary: | BACKGROUND Individualization of controlled ovarian stimulation (COS) for assisted conception is complicated by variable ovarian response to follicle stimulating hormone. We hypothesized that anti-Muellerian hormone (AMH), a predictor of oocyte yield, may facilitate treatment strategies for women undergoing COS, to optimize safety and clinical pregnancy rates.METHODS Prospective cohort study of 538 patients in two centres with differential COS strategies based on a centralized AMH measurement.RESULTS AMH was associated with oocyte yield after ovarian stimulation in both centres, and a 'reduced' AMH (1 to |
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ISSN: | 0268-1161 1460-2350 |
DOI: | 10.1093/humrep/den480 |