The Chemistry and Biology of Alkannin, Shikonin, and Related Naphthazarin Natural Products

Wound healing properties of plant extracts that contain the naphthoquinone natural products alkannin (1) and shikonin (2) have been known for many centuries. More recently, the biological properties of 1, 2, and related derivatives have been demonstrated experimentally, and their production both by...

Full description

Saved in:
Bibliographic Details
Published in:Angewandte Chemie International Edition 1999-02, Vol.38 (3), p.270-301
Main Authors: Papageorgiou, Vassilios P., Assimopoulou, Andreana N., Couladouros, Elias A., Hepworth, David, Nicolaou, K. C.
Format: Article
Language:English
Subjects:
Bioorganic chemistry
Natural products
Phytochemistry
Quinones
Wound healing
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Wound healing properties of plant extracts that contain the naphthoquinone natural products alkannin (1) and shikonin (2) have been known for many centuries. More recently, the biological properties of 1, 2, and related derivatives have been demonstrated experimentally, and their production both by cell cultures and chemical synthesis has been studied extensively.
ISSN:1433-7851
1521-3773
DOI:10.1002/(SICI)1521-3773(19990201)38:3<270::AID-ANIE270>3.0.CO;2-0