Systematic review of the mesopancreas: concept and clinical implications

Background In 2007, Gockel et al. coined the term mesopancreas (MP). In the next 10 years, a limited number of publications about MP have been published, but little is known about the oncological benefit of MP resection. We performed a systematic review of the literature on MP. Methods An electronic...

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Bibliographic Details
Published in:Clinical & translational oncology 2018-11, Vol.20 (11), p.1385-1391
Main Authors: Ramia, J. M., De-la-Plaza, R., Manuel-Vazquez, A., Lopez-Marcano, A., Morales, R.
Format: Article
Language:English
Subjects:
Humans
Medicine
Medicine & Public Health
Oncology
Pancreas - pathology
Pancreas - physiology
Pancreas - surgery
Pancreatic Neoplasms - prevention & control
Pancreatic Neoplasms - surgery
Pancreaticoduodenectomy - methods
Pancreaticoduodenectomy - trends
Research Article
Retrospective Studies
Terminology as Topic
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Summary:Background In 2007, Gockel et al. coined the term mesopancreas (MP). In the next 10 years, a limited number of publications about MP have been published, but little is known about the oncological benefit of MP resection. We performed a systematic review of the literature on MP. Methods An electronic search was performed in PubMed, EMBASE, Cochrane, Latindex, Scielo, and Koreamed databases until 15 June 2017 to identify all published articles dealing with the subject of MP. Some language restriction was done (Chinese and Rumanian). Results The search yielded 51 articles; 28 articles were selected as relevant. All were retrospective studies focused more on describing technical variants, feasibility and safety than on the cancer results. The R0 rate in patients with MP resection ranged between 57 and 96.7%. In all the articles with a control group, the R0 rate was higher in the MP excision group. Survival data were explicitly stated only in five series. Conclusion MP is a difficult-to-excise retropancreatic area. In theory, it is agreed that MP excision raises the rate of R0 resections, which in turn reflected in an improvement in the oncological results; however, at present there are no randomized studies to prove this. Achieving a worldwide consensus on its concept, landmarks, excision technique and oncological results is essential.
ISSN:1699-048X
1699-3055
DOI:10.1007/s12094-018-1869-5