Clinical practice guidelines for the diagnosis and treatment of cutaneous leishmaniasis in Turkey

Background Cutaneous leishmaniasis (CL) is a vector‐born parasitic disease characterized by various skin lesions that cause disfiguration if healed spontaneously. Although CL has been endemic for many years in the southern regions of Turkey, an increasing incidence in nonendemic regions is being obs...

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Published in:International journal of dermatology 2018-08, Vol.57 (8), p.973-982
Main Authors: Uzun, Soner, Gürel, Mehmet S., Durdu, Murat, Akyol, Melih, Fettahlıoğlu Karaman, Bilge, Aksoy, Mustafa, Aytekin, Sema, Borlu, Murat, İnan Doğan, Esra, Doğramacı, Çiğdem Asena, Kapıcıoğlu, Yelda, Akman‐Karakaş, Ayşe, Kaya, Tamer İ., Mülayim, Mehmet K., Özbel, Yusuf, Özensoy Töz, Seray, Özgöztaşı, Orhan, Yeşilova, Yavuz, Harman, Mehmet
Format: Article
Language:English
Subjects:
Antimony
Antimony compounds
Clinical practice guidelines
Complications
Cutaneous leishmaniasis
Delphi method
Diagnosis
Diagnostic systems
Guidelines
Lesions
Medical treatment
Parasitic diseases
Refugees
Skin diseases
Smear
Vector-borne diseases
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Summary:Background Cutaneous leishmaniasis (CL) is a vector‐born parasitic disease characterized by various skin lesions that cause disfiguration if healed spontaneously. Although CL has been endemic for many years in the southern regions of Turkey, an increasing incidence in nonendemic regions is being observed due to returning travelers and, more recently, due to Syrian refugees. Thus far, a limited number of national guidelines have been proposed, but no common Turkish consensus has emerged. Objectives The aim of this study was to develop diagnostic and therapeutic guidelines for the management of CL in Turkey. Methods This guideline is a consensus text prepared by 18 experienced CL specialists who have been working for many years in areas where the disease is endemic. The Delphi method was used to determine expert group consensus. Initially, a comprehensive list of items about CL was identified, and consensus was built from feedback provided by expert participants from the preceding rounds. Results Evidence‐based and expert‐based recommendations through diagnostic and therapeutic algorithms according to local availability and conditions are outlined. Conclusion Because CL can mimic many other skin diseases, early diagnosis and early treatment are very important to prevent complications and spread of the disease. The fastest and easiest diagnostic method is the leishmanial smear. The most common treatment is the use of local or systemic pentavalent antimony compounds.
ISSN:0011-9059
1365-4632
DOI:10.1111/ijd.14002