Components of the gene network associated with genotype-dependent response of wheat to the Fusarium mycotoxin deoxynivalenol

The Fusarium mycotoxin deoxynivalenol (DON) facilitates fungal spread within wheat tissue and the development of Fusarium head blight disease. The ability of wheat spikelets to resist DON-induced bleaching is genotype-dependent. In wheat cultivar (cv.) CM82036 DON resistance is associated with a qua...

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Bibliographic Details
Published in:Functional & integrative genomics 2008-11, Vol.8 (4), p.421-427
Main Authors: Walter, Stephanie, Brennan, Josephine M, Arunachalam, Chanemougasoundharam, Ansari, Khairul I, Hu, Xuejun, Khan, Mojibur R, Trognitz, Friederike, Trognitz, Bodo, Leonard, Gerald, Egan, Damian, Doohan, Fiona M
Format: Article
Language:English
Subjects:
Animal Genetics and Genomics
Biochemistry
Bioinformatics
Biological and medical sciences
Biomedical and Life Sciences
Cell Biology
Fhb1
Flowers & plants
Fundamental and applied biological sciences. Psychology
Fusarium
Fusarium - metabolism
Fusarium - pathogenicity
Gene Expression Profiling
Gene Expression Regulation, Plant
Gene Regulatory Networks
General aspects
Genomics
Genotype
Genotype & phenotype
Life Sciences
Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects)
Microbial Genetics and Genomics
Molecular Sequence Data
Mycotoxins - metabolism
Oligonucleotide Array Sequence Analysis
Pathogens
Plant Genetics and Genomics
Plant pathology
Short Communication
trichothecenes
Trichothecenes - metabolism
Triticum - genetics
Triticum - microbiology
Triticum aestivum
Wheat
Wheat cDNA microarray
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Summary:The Fusarium mycotoxin deoxynivalenol (DON) facilitates fungal spread within wheat tissue and the development of Fusarium head blight disease. The ability of wheat spikelets to resist DON-induced bleaching is genotype-dependent. In wheat cultivar (cv.) CM82036 DON resistance is associated with a quantitative trait locus, Fhb1, located on the short arm of chromosome 3B. Gene expression profiling (microarray and real-time RT-PCR analyses) of DON-treated spikelets of progeny derived from a cross between cv. CM82036 and the DON-susceptible cv. Remus discriminated ten toxin-responsive transcripts associated with the inheritance of DON resistance and Fhb1. These genes do not exclusively map to Fhb1. Based on the putative function of the ten Fhb1-associated transcripts, we discuss how cascades involving classical metabolite biotransformation and sequestration processes, alleviation of oxidative stress and promotion of cell survival might contribute to the host response and defence against DON.
ISSN:1438-793X
1438-7948
DOI:10.1007/s10142-008-0089-4