Penile Prosthesis in Solid Organ Transplant Recipients—A Matched Cohort Study

To determine whether patients with solid organ transplant (SOT) are at higher risk of developing complications after inflatable penile prosthesis (IPP) implantation. We retrospectively reviewed outcomes data for all patients with SOT who underwent IPP placement at our institution. A cohort of age-ma...

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Bibliographic Details
Published in:Urology (Ridgewood, N.J.) N.J.), 2018-07, Vol.117, p.86-88
Main Authors: Sun, Andrew Y., Babbar, Paurush, Gill, Bradley C., Angermeier, Kenneth W., Montague, Drogo K.
Format: Article
Language:English
Subjects:
Aged
Case-Control Studies
Follow-Up Studies
Humans
Male
Middle Aged
Organ Transplantation
Penile Implantation - adverse effects
Penile Prosthesis - adverse effects
Postoperative Complications - etiology
Reoperation
Retrospective Studies
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Summary:To determine whether patients with solid organ transplant (SOT) are at higher risk of developing complications after inflatable penile prosthesis (IPP) implantation. We retrospectively reviewed outcomes data for all patients with SOT who underwent IPP placement at our institution. A cohort of age-matched IPP recipients without SOT were used as controls. We identified 26 patients who underwent SOT and IPP between 1999 and 2015, and 26 controls. Transplants included heart (3), liver (2), kidney only (17), and kidney and pancreas (4). Mean follow-up time after IPP placement was 29.5 months (SOT group) and 13.5 months (controls). Age at IPP did not significantly differ between groups (53.7 + 8.1 vs 56.4 + 9.0, P = .26), nor did body mass index (30.3 + 5.5 vs 30.2 + 4.7, P = .92), history of prostatectomy (7.7% vs 15.4%, P = .39), rectal surgery (3.9% vs 3.9%, P = 1.00), hyperlipidemia (69.2% vs 69.2%, P = 1.00), hypertension (92.3% vs 76.9%, P = .25), or heart disease (57.7% vs 30.8%, P = .093). Peripheral vascular disease was more common in transplant patients (26.9% vs 3.9%, P = .021), as were stroke (19.2% vs 0.0%, P = .05) and diabetes (84.6% vs 53.6%, P = .016). No significant differences in IPP reoperation rates existed between patients with vs without SOT (11.5% vs 11.5%, P = 1.00), nor did they differ by organ transplanted (P = 1.00). No differences in IPP reoperation rate existed between 2-piece vs 3-piece IPP models (P = .47). Outcomes of IPP implantation in patients with SOT are similar to those of nontransplant patients. Patients with SOT should be considered suitable candidates for penile prosthesis.
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2018.03.048