Langerhans cell histiocytosis mimicking molluscum contagiosum: A case series

Langerhans cell histiocytosis (LCH) is a disorder characterized by accumulation of Langerhans‐like cells in one or various organs. A correct staging work‐up is essential since there are multiorgan presentations with a poor prognosis. We report three patients with LCH skin lesions mimicking molluscum...

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Bibliographic Details
Published in:Pediatric blood & cancer 2018-07, Vol.65 (7), p.e27047-n/a
Main Authors: Fernández Armenteros, José Manuel, Arco Huguet, Nuria, Sanmartin Novell, Veronica, Vilardell Villellas, Felip, Velasco Sanchez, Ana, Martró Català, Elisa, Martí Laborda, Rosa Maria, Soria Gili, Xavier
Format: Article
Language:English
Subjects:
Autoimmune diseases
Child, Preschool
Diagnosis, Differential
Female
Hematology
Histiocytosis
Histiocytosis, Langerhans-Cell - diagnosis
Histiocytosis, Langerhans-Cell - pathology
Humans
Infant
Langerhans cell histiocytosis
Lesions
Male
Mimicry
Molluscum contagiosum
Molluscum Contagiosum - diagnosis
Molluscum Contagiosum - pathology
multisystem disease
Oncology
Organs
Pediatrics
skin
Skin diseases
Skin Diseases - diagnosis
Skin Diseases - etiology
Skin Diseases - pathology
Viral infections
Young Adult
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Description
Summary:Langerhans cell histiocytosis (LCH) is a disorder characterized by accumulation of Langerhans‐like cells in one or various organs. A correct staging work‐up is essential since there are multiorgan presentations with a poor prognosis. We report three patients with LCH skin lesions mimicking molluscum contagiosum in association with both high and low risk organ involvement. This peculiar cutaneous presentation can be a clue for the diagnosis of LCH, a disease with potentially severe systemic involvement.
ISSN:1545-5009
1545-5017
DOI:10.1002/pbc.27047