Neutrophil‐lymphocyte ratio is associated with prognosis in patients who underwent potentially curative resection for gastric cancer

Background and Objectives The role of inflammation in cancer development is a well‐known phenomenon that may be represented by the neutrophil‐lymphocyte ratio (NLR). The present research intends to determine the impact of NLR on the survival outcome of patients with gastric cancer (GC), and to evalu...

Full description

Saved in:
Bibliographic Details
Published in:Journal of surgical oncology 2018-04, Vol.117 (5), p.851-857
Main Authors: Szor, Daniel José, Roncon Dias, Andre, Pereira, Marina A., Ramos, Marcus F.K.P., Zilberstein, Bruno, Cecconello, Ivan, Ribeiro, Ulysses
Format: Article
Language:English
Subjects:
Adenocarcinoma - mortality
Adenocarcinoma - pathology
Adenocarcinoma - surgery
Adult
Aged
Aged, 80 and over
Cancer surgery
Female
Follow-Up Studies
gastrectomy
Gastrectomy - mortality
Gastric cancer
Humans
Lymphatic system
Lymphocytes - pathology
Male
Medical prognosis
Middle Aged
Neutrophils
Neutrophils - pathology
neutrophil‐lymphocyte ratio
Prognosis
Retrospective Studies
Risk Factors
Stomach Neoplasms - mortality
Stomach Neoplasms - pathology
Stomach Neoplasms - surgery
Survival Rate
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background and Objectives The role of inflammation in cancer development is a well‐known phenomenon that may be represented by the neutrophil‐lymphocyte ratio (NLR). The present research intends to determine the impact of NLR on the survival outcome of patients with gastric cancer (GC), and to evaluate its use as a stratification factor for the staging groups. Methods Data regarding clinical characteristics, surgery, pathology, and follow‐up were retrospectively collected from our single‐center prospective database. Blood samples were obtained before surgery. Results A total of 383 patients (231 males) who underwent gastrectomy with lymphadenectomy were evaluated between 2009 and 2016. NLR established cutoff was 2.44, and patients were divided in NLR ≥2.44 (hNLR) and
ISSN:0022-4790
1096-9098
DOI:10.1002/jso.25036