Effect of hypercapnia on self-sustained muscle activity

•We measured self-sustained muscle activity of the triceps surae muscle.•Self-sustained muscle activity is generated by facilitation of plateau potentials in spinal motoneurons.•Self-sustained muscle activity was increased by CO2 rebreathing.•Motor neuromuscular activity in humans may be linked to t...

Full description

Saved in:
Bibliographic Details
Published in:Respiratory physiology & neurobiology 2018-04, Vol.250, p.24-30
Main Authors: Hatano, Kei, Shirakawa, Kazuki, Usuda, Noboru, Matsuura, Ryouta, Ohtsuka, Yoshinori, Yunoki, Takahiro
Format: Article
Language:English
Subjects:
Central chemoreceptor
Hypercapnia
Plateau potentials
Self-sustained muscle activity
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:•We measured self-sustained muscle activity of the triceps surae muscle.•Self-sustained muscle activity is generated by facilitation of plateau potentials in spinal motoneurons.•Self-sustained muscle activity was increased by CO2 rebreathing.•Motor neuromuscular activity in humans may be linked to the respiratory system, which is activated during hypercapnia. The aim of the present study was to determine the effect of hypercapnia on motor neuromuscular activity of the human triceps surae muscle. Nine subjects participated in trials in a normal breathing condition and a CO2 rebreathing condition. In both conditions, in order to provoke self-sustained muscle activity, percutaneous electrical train stimulation was applied to the tibial nerve while each subject lay on a bed. Self-sustained muscle activity, which is an indirect observation of plateau potentials in spinal motoneurons, was measured for 30 s after the train stimulation by using surface electromyography. The sustained muscle activity was increased by CO2 rebreathing (P 
ISSN:1569-9048
1878-1519
DOI:10.1016/j.resp.2018.02.002