The cardiac troponin response following physical exercise in relation to biomarker criteria for acute myocardial infarction; the North Sea Race Endurance Exercise Study (NEEDED) 2013

The aim of this study was to investigate troponin (cTn) dynamics for both genders, compared the different release patterns to the gender specific 99th percentile and to current biomarker criteria for diagnosing myocardial infarction (MI). Serum was collected from 97 recreational cyclists 24 h before...

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Bibliographic Details
Published in:Clinica chimica acta 2018-04, Vol.479, p.155-159
Main Authors: Skadberg, Øyvind, Kleiven, Øyunn, Ørn, Stein, Bjørkavoll-Bergseth, Magnus F., Melberg, Tor H., Omland, Torbjørn, Aakre, Kristin M.
Format: Article
Language:English
Subjects:
Cardiac biomarker
Dynamics
Endurance exercise
Healthy
Reference interval
Release
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Summary:The aim of this study was to investigate troponin (cTn) dynamics for both genders, compared the different release patterns to the gender specific 99th percentile and to current biomarker criteria for diagnosing myocardial infarction (MI). Serum was collected from 97 recreational cyclists 24 h before and immediately, 3 and 24 h following a 91-km bike race. hs-cTnI (Abbott) and hs-cTnT (Roche) were measured. Conventional or CT coronary angiography was performed in the 13 participants with the highest hs-cTnI (>140 ng/L). Three subjects with obstructive coronary artery disease were excluded from the statistical analysis. There was a significant (p 
ISSN:0009-8981
1873-3492
DOI:10.1016/j.cca.2018.01.033