Best practice perioperative strategies and surgical techniques for preventing caesarean section surgical site infections: a systematic review of reviews and meta‐analyses

Background Surgical site infection (SSI) following caesarean section is a problem for women and health services. Caesarean section is a high volume procedure and the estimated incidence of SSI may be as high as 9%. Objectives The objective of this study was to identify a suite of perioperative strat...

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Bibliographic Details
Published in:BJOG : an international journal of obstetrics and gynaecology 2018-07, Vol.125 (8), p.956-964
Main Authors: Martin, EK, Beckmann, MM, Barnsbee, LN, Halton, KA, Merollini, KMD, Graves, N
Format: Article
Language:English
Subjects:
Anti-Infective Agents, Local - administration & dosage
Antibiotic Prophylaxis - methods
Antibiotics
Best practice
caesarean section
Cesarean section
Cesarean Section - adverse effects
Data processing
Disease control
Endometritis
Endometritis - etiology
Endometritis - prevention & control
evidence synthesis
Evidence-based medicine
Female
healthcare‐associated infection
Humans
Infections
Iodine
Literature reviews
Nosocomial infections
Perioperative Care - methods
Placenta
Povidone
Pregnancy
Prophylaxis
Reviews
surgical site infection
Surgical site infections
Surgical techniques
Surgical Wound Infection - etiology
Surgical Wound Infection - prevention & control
Systematic review
Vagina
Vagina - surgery
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Summary:Background Surgical site infection (SSI) following caesarean section is a problem for women and health services. Caesarean section is a high volume procedure and the estimated incidence of SSI may be as high as 9%. Objectives The objective of this study was to identify a suite of perioperative strategies and surgical techniques that reduce the risk of SSI following caesarean section. Search strategy Six electronic databases were searched to systematically review literature reviews, systematic reviews and meta‐analyses published from 2006 to 2016. Search terms included: endometritis, SSI, caesarean section, meta‐analysis, review, systematic. Selection criteria Studies were sought in which competing perioperative strategies and surgical techniques relevant for caesarean section were identified and quantifiable infection outcomes were reported. General infection control strategies were excluded. Data collection and analysis Data on study characteristics and clinical effectiveness were extracted. Quality, including bias within individual studies, was examined using a modified A Measurement Tool to Assess Systematic Reviews (AMSTAR) checklist. Recommendations for SSI risk‐reducing strategies were developed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Main results Of 466 records retrieved, 44 studies were selected for the evidence synthesis. Recommended strategies were: administer pre‐incision antibiotic prophylaxis, prepare the vagina with iodine‐povidone solution and spontaneous placenta removal. Conclusions We recommend clinicians implement pre‐incision antibiotic prophylaxis, vaginal preparation and spontaneous placenta removal as an infection control bundle for caesarean section. Funding Queensland University of Technology. Tweetable Infection control for caesarean: pre‐incision AB prophylaxis, vaginal prep, spontaneous placenta removal. Tweetable Infection control for caesarean: pre‐incision AB prophylaxis, vaginal prep, spontaneous placenta removal. This paper includes Author Insights, a video available at https://vimeo.com/rcog/authorinsights15125
ISSN:1470-0328
1471-0528
DOI:10.1111/1471-0528.15125