Fast matrix digestion with hot ethanolic alkali plus pyrogallol for polychlorinated dibenzo- p-dioxins, polychlorinated dibenzofurans and coplanar polychlorinated biphenyls analysis in biological samples

The efficiency of hot alkaline digestion of a sample matrix was investigated for determination of polychlorinated dibenzo- p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and coplanar polychlorinated biphenyls (CoPCBs) in biological samples. Results of recovery tests of octachlorodibenzofur...

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Bibliographic Details
Published in:Analytica chimica acta 2004-04, Vol.509 (1), p.21-26
Main Authors: Otaka, Hiroaki, Hashimoto, Shunji
Format: Article
Language:English
Subjects:
Alkaline digestion
Analytical chemistry
Chemistry
Chromatographic methods and physical methods associated with chromatography
Coplanar polychlorinated biphenyls
Dechlorination
Exact sciences and technology
Gas chromatographic methods
Polychlorinated dibenzo- p-dioxins
Polychlorinated dibenzofurans
Pyrogallol
Spectrometric and optical methods
Thunnus
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Summary:The efficiency of hot alkaline digestion of a sample matrix was investigated for determination of polychlorinated dibenzo- p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and coplanar polychlorinated biphenyls (CoPCBs) in biological samples. Results of recovery tests of octachlorodibenzofuran (OCDF) after spiking into lean tuna showed degradation of OCDF and the production of a large quantity of lower-chlorinated dibenzofurans (LoCDFs) when the sample was digested with hot ethanolic KOH. However, it was also confirmed that pyrogallol (PG) prevented dechlorination of OCDF. The accuracy of the hot alkaline digestion method with PG was demonstrated by analyzing PCDD/Fs-spiked lean tuna. The proposed method is more suitable than conventional versions for the determination of dioxins in biological samples in terms of savings in time, adequate digestion of matrix and high degree of recovery of internal standards.
ISSN:0003-2670
1873-4324
DOI:10.1016/j.aca.2003.12.016