The association of schizophrenia with chronic non transmissible diseases

The life expectancy of patients with schizophrenia (SCH) is 11 to 20 years less than the general population. There is an association between SCH and various diseases and chronic conditions, highlighting the cardio-metabolic diseases. This association has been attributed to the use of antipsychotics,...

Full description

Saved in:
Bibliographic Details
Published in:Revista medíca de Chile 2017-08, Vol.145 (8), p.1047-1053
Main Authors: Orellana, Gricel, Rodríguez, Matías, González, Nicolás, Durán, Eduardo
Format: Article
Language:Spanish
Subjects:
Antipsychotic Agents - adverse effects
Cardiovascular Diseases - etiology
Chronic Disease
Humans
Life Expectancy
Metabolic Syndrome - etiology
Osteoporosis - etiology
Renal Insufficiency, Chronic - etiology
Risk Factors
Schizophrenia - complications
Schizophrenia - drug therapy
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The life expectancy of patients with schizophrenia (SCH) is 11 to 20 years less than the general population. There is an association between SCH and various diseases and chronic conditions, highlighting the cardio-metabolic diseases. This association has been attributed to the use of antipsychotics, however, evidence has also shown intrinsic susceptibility of schizophrenic patients the development of chronic conditions. This review aims to update knowledge about chronic conditions such as cardiometabolic risk and sleep, bone and kidney disorders related to SCH. These patients have a high prevalence of risk behaviors, including smoking and poor diet. They have a worse metabolic profile than the general population and a greater likelihood of developing metabolic syndrome, diabetes and cardiovascular disease. SCH has also been associated with other chronic diseases such as osteoporosis and chronic kidney disease. The high prevalence of these comorbidities in schizophrenic population is not explained solely by the antipsychotic treatment, therefore intrinsic mechanisms associated to SCH are postulated to be associated with these conditions. This new information requires a change in the multidisciplinary medical approach for the study and management of schizophrenic patients.
ISSN:0717-6163
DOI:10.4067/s0034-98872017000801047