Symptom Burden Clustering in Chronic Kidney Disease Stage 5

Patients with chronic kidney disease (CKD) Stage 5, experience multiple symptoms that negatively affect the health-related quality of life (HRQoL). This study examined the cluster of symptoms and their association with disease severity and comorbidities. The study sample included 123 patients with C...

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Bibliographic Details
Published in:Clinical nursing research 2019-06, Vol.28 (5), p.583-601
Main Authors: Gutiérrez Sánchez, Daniel, Leiva-Santos, Juan P., Cuesta-Vargas, Antonio I.
Format: Article
Language:English
Subjects:
Chronic illnesses
Clinical assessment
Clinical research
Clustering
Comorbidity
Correlation analysis
Dialysis
Health status
Kidney diseases
Mental depression
Multiple symptoms
Nursing
Palliative care
Quality of life
Severity
Sleep disorders
Strength
Symptom management
Symptoms
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Summary:Patients with chronic kidney disease (CKD) Stage 5, experience multiple symptoms that negatively affect the health-related quality of life (HRQoL). This study examined the cluster of symptoms and their association with disease severity and comorbidities. The study sample included 123 patients with CKD Stage 5; 60 patients were in the dialysis group and 63 patients in the Conservative Kidney Management group. Symptom data were collected using the Spanish modified version of Palliative Care Outcome Scale–Symptoms (POS-S) Renal, a validated questionnaire to assess symptoms in this population. More than half of the patients described weakness, difficulty sleeping, and feeling depressed. Two symptom clusters were identified. There was no significant statistical correlation between disease severity and symptoms and between comorbidities and symptoms. The tendency of these symptoms to occur together has implications for improving symptom management in this population. Routine symptom assessment can be useful in clinical and research settings.
ISSN:1054-7738
1552-3799
DOI:10.1177/1054773817740671