Quality of life in HIV subtype C infection among asymptomatic subjects and its association with CD4 counts and viral loads - a studyfrom South India

Objective: To study the association between quality of life (QOL) domains and biological markers of disease progression of HIV infection, i.e. viral load (VL) and CD4 counts among asymptomatic subjects with HIV subtype C infection in South India. Design: Quality of life was measured using the locall...

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Bibliographic Details
Published in:Quality of life research 2006-12, Vol.15 (10), p.1597-1605
Main Authors: Chandra, Prabha S, Gandhi, Charu, Satishchandra, P, Kamat, Anupa, Desai, Anita, Ravi, V, Ownby, Raymond L, Subbakrishna, D K, Kumar, Mahendra
Format: Article
Language:English
Subjects:
Human immunodeficiency virus
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Summary:Objective: To study the association between quality of life (QOL) domains and biological markers of disease progression of HIV infection, i.e. viral load (VL) and CD4 counts among asymptomatic subjects with HIV subtype C infection in South India. Design: Quality of life was measured using the locally validated version of the WHOQOL HIV-BREF. The subjects were neurologically asymptomatic, non psychiatrically ill HIV infected men and women participating in a cohort study. Results: The results indicated mixed findings, with some QOL dimensions being associated with high VLs and low CD4 counts while several others did not show any associations. Significant associations were seen between low CD4 counts and the psychological and social relationships domain, with lower mean scores in these domains being reported by subjects having CD4 counts
ISSN:0962-9343
1573-2649
DOI:10.1007/s11136-006-9001-7