Real-world outcomes of surgery for native mitral valve endocarditis

Consensus guidelines recommend repair over replacement for the surgical treatment of active native mitral valve infective endocarditis. However, contemporary practice and long-term outcome data are limited. Multivariable Cox regression was used to compare outcomes of 1970 patients undergoing isolate...

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Bibliographic Details
Published in:The Journal of thoracic and cardiovascular surgery 2017-12, Vol.154 (6), p.1906-1912.e9
Main Authors: Toyoda, Nana, Itagaki, Shinobu, Egorova, Natalia N., Tannous, Henry, Anyanwu, Anelechi C., El-Eshmawi, Ahmed, Adams, David H., Chikwe, Joanna
Format: Article
Language:English
Subjects:
California
endocarditis
Endocarditis - surgery
Endocarditis, Bacterial - surgery
Humans
Mitral Valve
mitral valve endocarditis
mitral valve repair
mitral valve replacement
New York
Reoperation
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Summary:Consensus guidelines recommend repair over replacement for the surgical treatment of active native mitral valve infective endocarditis. However, contemporary practice and long-term outcome data are limited. Multivariable Cox regression was used to compare outcomes of 1970 patients undergoing isolated primary mitral valve repair (n = 367, 19%) or replacement (n = 1603, 81%) for active infective endocarditis between 1998 and 2010 in New York and California states. The primary outcome was long-term survival. Secondary outcomes were recurrent endocarditis and mitral reoperation. Median follow-up time was 6.6 years (range 0-12), and last follow-up date was December 31, 2015. Mitral valve repair rates increased from 10.7% to 19.4% over the study period (P 
ISSN:0022-5223
1097-685X
DOI:10.1016/j.jtcvs.2017.07.077