Proposal of a novel clinical score to predict heart failure incidence in long-term survivors of acute coronary syndromes

HF remains a frequent complication following MI and adversely affects prognosis. The objective of this study was to identify predictors of HF following MI and to design a risk score for its prediction. Retrospective study of all consecutive patients admitted for MI. Primary end point was time to inc...

Full description

Saved in:
Bibliographic Details
Published in:International journal of cardiology 2017-12, Vol.249, p.301-307
Main Authors: Rodríguez-Mañero, Moisés, Cordero, Alberto, Kreidieh, Omar, García-Acuña, Jose Mª., Seijas, Jose, Agra-bermejo, Rosa María, Abou-Jokh, Charigan, Álvarez-Rodríguez, Leyre, Álvarez-Iglesias, Diego, López-Palop, Ramón, Cid, Belen, Carrillo, Pilar, González-Juanatey, Jose R.
Format: Article
Language:English
Subjects:
Acute Coronary Syndrome - diagnosis
Acute Coronary Syndrome - physiopathology
Acute Coronary Syndrome - therapy
Aged
Aged, 80 and over
Coronary artery disease
Female
Follow-Up Studies
Heart failure
Heart Failure - diagnosis
Heart Failure - physiopathology
Heart Failure - therapy
Humans
Incidence
Male
Middle Aged
Myocardial infarction
Predictive Value of Tests
Retrospective Studies
Severity of Illness Index
Survivors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:HF remains a frequent complication following MI and adversely affects prognosis. The objective of this study was to identify predictors of HF following MI and to design a risk score for its prediction. Retrospective study of all consecutive patients admitted for MI. Primary end point was time to incident HF. Patients with previous history of HF were excluded. Death was modelled as competing risk. 5737 patients were included. Mean age was 66.32±12.80. During a median follow-up of 47.0months (23.0–73.0), 686 patients (12%) developed HF. Age, diabetes mellitus, peripheral artery disease, renal insufficiency, chronic obstructive pulmonary disease, persistent atrial fibrillation, haemoglobin, troponin peak, diuretic at admission, ventricular function, and revascularization were independent predictors for HF development. According to this multivariate regression analysis, we developed a novel score that allows for the identification of patients at high (≥16), medium (9–15) and low risk (
ISSN:0167-5273
1874-1754
DOI:10.1016/j.ijcard.2017.07.084