Green approach for one-pot synthesis of silver nanorod using cellulose nanocrystal and their cytotoxicity and antibacterial assessment

•Fast and green synthesis of Ag nanorods in powder form through by novel approach.•Using of cellulose nanocrystals as a mediator for synthesis of Ag nanorods.•Investigating their antibacterial activity toward prokaryotic cells.•Assessment the cytotoxicity of Ag nanorods towards eukaryotic cells. Her...

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Bibliographic Details
Published in:International journal of biological macromolecules 2018-01, Vol.106, p.784-792
Main Authors: Shaheen, Th. I., Fouda, Amr
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - chemical synthesis
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - pharmacology
Antibacterial and cytotoxicity
Cell Proliferation - drug effects
Cellulose - chemical synthesis
Cellulose - chemistry
Cellulose - pharmacology
Cellulose nanocrystals
Gram-Negative Bacteria - drug effects
Gram-Negative Bacteria - pathogenicity
Gram-Positive Bacteria - drug effects
Gram-Positive Bacteria - pathogenicity
Green Chemistry Technology
Humans
Metal Nanoparticles - administration & dosage
Metal Nanoparticles - chemistry
Microbial Sensitivity Tests
Nanoparticles - administration & dosage
Nanoparticles - chemistry
Nanotubes - chemistry
Silver - chemistry
Silver nanorods
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Summary:•Fast and green synthesis of Ag nanorods in powder form through by novel approach.•Using of cellulose nanocrystals as a mediator for synthesis of Ag nanorods.•Investigating their antibacterial activity toward prokaryotic cells.•Assessment the cytotoxicity of Ag nanorods towards eukaryotic cells. Herein, this research addresses an innovative approach for one-pot synthesis of highly stabilized silver nanorods in powder form at concentration as high as feasible to be proposed in large-scale production via cellulose nanocrystals (CNC). For the first time, CNC without any surface modification in the presence of alkali is acting as both reducing and stabilizing agent for assembling of Ag nanorods. Extraction of CNC from cotton is carried out as per to acid hydrolysis technique. Thorough assessments of Ag nanorods formation, structural and morphological characteristics of Ag nanorods were investigated by making use of UV–vis spectroscopy, TEM, DLS, AFM and X-ray diffraction (XRD) analysis. Also, the antibacterial activity and cytotoxicity of Ag nanorod were investigated. Research outputs signify that, Ag nanorods has been successfully prepared through an effectively approach by virtue of the textural feature of CNC as a mediator. Results revealed the great tendency of CNC toward reducing and stabilizing the as formed Ag nanorods even at high concentration. Results also demonstrated that Ag nanorods have not merely remarkably antibacterial activity towards Gram-positive and Gram-negative bacteria, but safe for using in human life, which exhibited no effect on eukaryotic cells.
ISSN:0141-8130
1879-0003
DOI:10.1016/j.ijbiomac.2017.08.070