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Enhancing the solubility and bioactivity of anticancer drug tamoxifen by water-soluble pillar[6]arene-based host-guest complexation

A water-soluble pillar[6]arene functions as a solubilizing agent to enhance the solubility and bioactivity of poorly water-soluble anticancer drug tamoxifen by host-guest complexation between it and tamoxifen.

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2017-08, Vol.53 (70), p.9749-9752
Main Authors: Shangguan, Liqing, Chen, Qi, Shi, Bingbing, Huang, Feihe
Format: Article
Language:English
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Description
Summary:A water-soluble pillar[6]arene functions as a solubilizing agent to enhance the solubility and bioactivity of poorly water-soluble anticancer drug tamoxifen by host-guest complexation between it and tamoxifen.
ISSN:1359-7345
1364-548X
DOI:10.1039/c7cc05305c