Feasibility of a wait‐and‐scan period as initial management strategy for head and neck paraganglioma

Background The main goal of head and neck paraganglioma (PGL) management is reduction of treatment‐induced and tumor‐induced complications. In the current study, tumor growth rates and tumor‐induced complications during a wait‐and‐scan period are evaluated. Methods This was a retrospective cohort st...

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Bibliographic Details
Published in:Head & neck 2017-10, Vol.39 (10), p.2088-2094
Main Authors: Jansen, Thijs T. G., Timmers, Henri J. L. M., Marres, Henri A. M., Kunst, Henricus P. M.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Carotid body
Cohort Studies
Feasibility Studies
Female
Follow-Up Studies
Growth rate
Head and neck
Head and Neck Neoplasms - complications
Head and Neck Neoplasms - pathology
Head and Neck Neoplasms - therapy
Humans
Magnetic Resonance Imaging - methods
Male
management
Middle Aged
Mutation
Neuroendocrine tumors
Paraganglioma
Paraganglioma - complications
Paraganglioma - pathology
Paraganglioma - therapy
Retrospective Studies
Succinate Dehydrogenase - genetics
Tumors
Vagus nerve
wait‐and‐scan
Watchful Waiting - methods
Young Adult
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Summary:Background The main goal of head and neck paraganglioma (PGL) management is reduction of treatment‐induced and tumor‐induced complications. In the current study, tumor growth rates and tumor‐induced complications during a wait‐and‐scan period are evaluated. Methods This was a retrospective cohort study. Tumor growth was measured in axial plane diameter and tumor volume. Results Of 59 jugulotympanic tumors, 71 carotid body tumors, and 29 vagal body tumors, 44% were growing (median follow‐up of 63.6 months). Median growth rates were 0.41 mm/year (range 0–439 mm), 1.6 mm/year (range 0–23.68 mm), and 1.6 mm/year (range 0–23.68 mm) respectively. Growth was significantly correlated to age at presentation (odds ratio [OR] = 0.974; P 
ISSN:1043-3074
1097-0347
DOI:10.1002/hed.24871