Exercise training improves functional status in hypertensive older adults under angiotensin converting enzymes inhibitors medication

The study aims to analyze the effect of three types of treatment on functional status, and cardiovascular risk outcomes in hypertensive older adults with comorbidities. Participants (n=418) underwent one of the following 3 conditions: i) multicomponent exercise training 3 times/week (MEX; n=116); ii...

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Bibliographic Details
Published in:Experimental gerontology 2018-08, Vol.109, p.82-89
Main Authors: Baptista, Liliana C., Machado-Rodrigues, Aristides M., Veríssimo, Manuel Teixeira, Martins, Raul A.
Format: Article
Language:English
Subjects:
Angiotensin converting enzyme inhibitors
Cardiovascular risk factors
Exercise
Functional status
Physical health related quality of life
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Summary:The study aims to analyze the effect of three types of treatment on functional status, and cardiovascular risk outcomes in hypertensive older adults with comorbidities. Participants (n=418) underwent one of the following 3 conditions: i) multicomponent exercise training 3 times/week (MEX; n=116); ii) angiotensin converting enzyme inhibitors used mono-dose daily (ACEi; n=70); iii) combined exercise and ACEi drugs (ACEiMEX; n=232). The trial was completed by 82% of the participants (n=342): MEX (n=90); ACEi (n=66); ACEiMEX (n=186). Baseline and 2-year follow-up evaluations included the Senior Fitness Test battery, Short Form Health Survey 36 (SF-36), the health history questionnaires, anthropometric and hemodynamic profile. MEX and ACEiMEX groups improved all physical functional status outcomes, decreased systolic (SBP) and diastolic blood pressure (p
ISSN:0531-5565
1873-6815
DOI:10.1016/j.exger.2017.06.013