Who is most affected by prenatal alcohol exposure: Boys or girls?

Highlights • Prenatal maternal alcohol use affects both sexes similarly on most variables. • Girls had significantly more overall dysmorphology and worse cognitive outcomes. • Prenatal bingeing of 6+ drinks is associated with fewer males alive at age seven. • Controlling for 13 covariates, girls hav...

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Bibliographic Details
Published in:Drug and alcohol dependence 2017-08, Vol.177, p.258-267
Main Authors: May, Philip A, Tabachnick, Barbara, Hasken, Julie M, Marais, Anna-Susan, de Vries, Marlene M, Barnard, Ronel, Joubert, Belinda, Cloete, Marise, Botha, Isobel, Kalberg, Wendy O, Buckley, David, Burroughs, Zachary R, Bezuidenhout, Heidre, Robinson, Luther K, Manning, Melanie A, Adnams, Colleen M, Seedat, Soraya, Parry, Charles D.H, Hoyme, H. Eugene
Format: Article
Language:English
Subjects:
Alcohol Drinking - adverse effects
Alcohol Drinking - epidemiology
Alcohol Drinking - psychology
Alcohol use
Alcoholic beverages
Binge drinking
Boys and girls
Case-Control Studies
Child
Childbirth & labor
Clinical outcomes
Cognition
Diagnosis
Drinking behavior
Dysmorphology
Exposure
Female
Fetal alcohol spectrum disorders
Fetal Alcohol Spectrum Disorders - diagnosis
Fetal Alcohol Spectrum Disorders - epidemiology
Fetal Alcohol Spectrum Disorders - psychology
Fetal alcohol syndrome
Girls
Humans
Intelligence Tests
Male
Males
Medical diagnosis
Neurobehavior
Neurobehavioral functioning
Neurocognition
Neuropsychological Tests
Postpartum
Pregnancy
Prenatal alcohol exposure
Prenatal care
Prenatal experience
Prenatal exposure
Prenatal Exposure Delayed Effects - diagnosis
Prenatal Exposure Delayed Effects - epidemiology
Prenatal Exposure Delayed Effects - psychology
Psychiatry
Quality
Regression analysis
Risk analysis
Risk factors
Sex
Sex Characteristics
Sex ratio
Survival
Viability
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Summary:Highlights • Prenatal maternal alcohol use affects both sexes similarly on most variables. • Girls had significantly more overall dysmorphology and worse cognitive outcomes. • Prenatal bingeing of 6+ drinks is associated with fewer males alive at age seven. • Controlling for 13 covariates, girls have a higher probability for fetal alcohol spectrum disorders (FASD).
ISSN:0376-8716
1879-0046
DOI:10.1016/j.drugalcdep.2017.04.010