Efficacy of peeling during different periods of the menstrual cycle on acne

The aim of this study was to investigate the efficacy of 50% glycolic acid peeling performed at different phases of menstruation on acne. This study included 30 patients with mild-to-moderate acne. Those with regular menstrual cycles and no history or laboratory evidence of hormonal pathology, hirsu...

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Bibliographic Details
Published in:Journal of cosmetic and laser therapy 2017-10, Vol.19 (6), p.373-375
Main Authors: Bulbul Baskan, Emel, Tilki Günay, Işıl, Saricaoglu, Hayriye
Format: Article
Language:English
Subjects:
Acne Vulgaris - therapy
Adult
Chemexfoliation - methods
Female
Glycolates - therapeutic use
Humans
Menstrual Cycle - metabolism
Ovulation - metabolism
Young Adult
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Summary:The aim of this study was to investigate the efficacy of 50% glycolic acid peeling performed at different phases of menstruation on acne. This study included 30 patients with mild-to-moderate acne. Those with regular menstrual cycles and no history or laboratory evidence of hormonal pathology, hirsutism were selected. Thirty patients were divided in three groups. The first group received peeling applications in the first 7 days of menstruation; the second group received the peel between 10 and 14 days; and the third group received the peel during the last 10 days of menstruation. The 30 female patients included in study. All patients' menstrual cycles were regular. All groups were homogenous in terms of initial acne severity scores. Acne severity scores decreased in all groups after 3 months of therapy; statistically significant differences were achieved only in the second group. The results of our study suggest that chemical peeling administered during ovulation provides the most significant benefit for acne lesions. Ovulation is the period when estrogen reaches its highest level. Estrogen decreases sebum production through different mechanisms. The beneficial effects of estrogen on acne and healing in combination with those of chemical peeling may cause synergistic therapeutic effects with pronounced results.
ISSN:1476-4172
1476-4180
DOI:10.1080/14764172.2017.1334926