Microenvironment of Liver Regeneration in Liver Cancer

The occurrence and development of liver cancer are essentially the most serious outcomes of uncontrolled liver regeneration. The progression of liver cancer is inevitably related to the abnormal microenvironment of liver regeneration. The deterioration observed in the microenvironment of liver regen...

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Bibliographic Details
Published in:Chinese journal of integrative medicine 2017-07, Vol.23 (7), p.555-560
Main Authors: Li, Han-min, Ye, Zhi-hua
Format: Article
Language:English
Subjects:
Academic Exploration
Humans
Liver Neoplasms - pathology
Liver Neoplasms - physiopathology
Liver Neoplasms - prevention & control
Liver Neoplasms - therapy
Liver Regeneration
Medicine
Medicine & Public Health
Medicine, Chinese Traditional
Neoplasm Metastasis
Neoplasm Recurrence, Local - pathology
Tumor Microenvironment
微环境
时间序列
治疗
综合调节
肝再生
肝癌
肝脏再生
肿瘤发生
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Summary:The occurrence and development of liver cancer are essentially the most serious outcomes of uncontrolled liver regeneration. The progression of liver cancer is inevitably related to the abnormal microenvironment of liver regeneration. The deterioration observed in the microenvironment of liver regeneration is a necessary condition for the occurrence, development and metastasis of cancer. Therefore, the use of a technique to prevent and treat liver cancer via changes in the microenvironment of liver regeneration is a novel strategy. This strategy would be an effective way to delay, prevent or even reverse cancer occurrence, development and metastasis through an improvement in the liver regeneration microenvironment along with the integrated regulation of multiple components, targets, levels, channels and time sequences. In addition, the treatment of ＂tonifying Shen（Kidney） to regulate liver regeneration and repair by affecting stem cells and their microenvironment＂ can regulate ＂the dynamic imbalance between the normal liver regeneration and the abnormal liver regeneration＂; this would improve the microenvironment of liver regeneration, which is also a mechanism by which liver cancer may be prevented or treated.
ISSN:1672-0415
1993-0402
DOI:10.1007/s11655-017-2806-0