Indirect (herd) protection, following pneumococcal conjugated vaccines introduction: A systematic review of the literature

Highlights • This is a systemic literature review on PCV indirect (herd) impact in adults. • Adults IPD and pneumonia rates decreased in most countries post-PCV introduction. • Herd protection depended on PCV uptake rates and time from PCV implementation. • Adults >65 years old seem to benefit th...

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Bibliographic Details
Published in:Vaccine 2017-05, Vol.35 (22), p.2882-2891
Main Authors: Tsaban, Gal, Ben-Shimol, Shalom
Format: Article
Language:English
Subjects:
Adolescent
Adult
Adults
Age
Age Factors
Aged
Aged, 80 and over
Allergy and Immunology
Canada - epidemiology
Child
Child, Preschool
Children
Cost analysis
Disease
Epidemiology
Female
Herd protection
Humans
Immunity, Herd
Immunization
Immunization Programs
Indirect immunity
Invasive pneumococcal disease (IPD)
Laboratories
Literature reviews
Male
Meningitis
Middle Aged
Morbidity
Older people
Pneumococcal conjugated vaccine (PCV)
Pneumococcal Infections - epidemiology
Pneumococcal Infections - immunology
Pneumococcal Infections - prevention & control
Pneumococcal Vaccines - administration & dosage
Pneumococcal Vaccines - immunology
Pneumonia
Pneumonia, Pneumococcal - epidemiology
Pneumonia, Pneumococcal - microbiology
Pneumonia, Pneumococcal - prevention & control
Population
Statistical analysis
Streptococcus infections
Streptococcus pneumoniae - immunology
Studies
Surveillance
Systematic review
Vaccination
Vaccines
Vaccines, Conjugate - administration & dosage
Vaccines, Conjugate - immunology
Young Adult
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Description
Summary:Highlights • This is a systemic literature review on PCV indirect (herd) impact in adults. • Adults IPD and pneumonia rates decreased in most countries post-PCV introduction. • Herd protection depended on PCV uptake rates and time from PCV implementation. • Adults >65 years old seem to benefit the most from PCV introduction.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2017.04.032