Association between active commuting and incident cardiovascular disease, cancer, and mortality: prospective cohort study

Objective To investigate the association between active commuting and incident cardiovascular disease (CVD), cancer, and all cause mortality.Design Prospective population based study. Setting UK Biobank.Participants 263 450 participants (106 674 (52%) women; mean age 52.6), recruited from 22 sites a...

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Bibliographic Details
Published in:BMJ (Online) 2017-04, Vol.357, p.j1456-j1456
Main Authors: Celis-Morales, Carlos A, Lyall, Donald M, Welsh, Paul, Anderson, Jana, Steell, Lewis, Guo, Yibing, Maldonado, Reno, Mackay, Daniel F, Pell, Jill P, Sattar, Naveed, Gill, Jason M R
Format: Article
Language:English
Subjects:
Accelerometers
Adult
Aged
Bicycling - statistics & numerical data
Biobanks
Body mass index
Cancer
Cardiovascular disease
Cardiovascular Diseases - epidemiology
Cohort analysis
Commuting
Diabetes
Ethnicity
Exercise
Female
Follow-Up Studies
Hospitals
Humans
Hypertension
Incidence
Male
Middle Aged
Mortality
Neoplasms - epidemiology
Physical fitness
Proportional Hazards Models
Prospective Studies
Public transportation
Questionnaires
Socioeconomic Factors
Transportation - methods
United Kingdom
Walking - statistics & numerical data
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Summary:Objective To investigate the association between active commuting and incident cardiovascular disease (CVD), cancer, and all cause mortality.Design Prospective population based study. Setting UK Biobank.Participants 263 450 participants (106 674 (52%) women; mean age 52.6), recruited from 22 sites across the UK. The exposure variable was the mode of transport used (walking, cycling, mixed mode v non-active (car or public transport)) to commute to and from work on a typical day.Main outcome measures Incident (fatal and non-fatal) CVD and cancer, and deaths from CVD, cancer, or any causes.Results 2430 participants died (496 were related to CVD and 1126 to cancer) over a median of 5.0 years (interquartile range 4.3-5.5) follow-up. There were 3748 cancer and 1110 CVD events. In maximally adjusted models, commuting by cycle and by mixed mode including cycling were associated with lower risk of all cause mortality (cycling hazard ratio 0.59, 95% confidence interval 0.42 to 0.83, P=0.002; mixed mode cycling 0.76, 0.58 to 1.00, P
ISSN:0959-8138
1756-1833
DOI:10.1136/bmj.j1456