Potentially inappropriate medicines in elderly hospitalised patients according to the EU(7)-PIM list, STOPP version 2 criteria and comprehensive protocol

Purpose The aim of this study was to measure the prevalence of potentially inappropriate medications (PIMs) by using the EU(7)-PIM list, STOPP (Screening Tool of Older Persons’ potentially inappropriate Prescriptions) version 2 criteria and the new comprehensive protocol. Methods This prospective st...

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Bibliographic Details
Published in:European journal of clinical pharmacology 2017-08, Vol.73 (8), p.991-999
Main Authors: Mucalo, Iva, Hadžiabdić, Maja Ortner, Brajković, Andrea, Lukić, Sonja, Marić, Patricia, Marinović, Ivana, Bačić-Vrca, Vesna
Format: Article
Language:English
Subjects:
Age
Aged
Aged, 80 and over
Biomedical and Life Sciences
Biomedicine
Criteria
Croatia
Female
Geriatrics
Glomerular filtration rate
Hospitalization
Hospitals, University - statistics & numerical data
Humans
Inappropriate Prescribing - statistics & numerical data
Male
Older people
Patient safety
Patients
Pharmacoepidemiology and Prescription
Pharmacology
Pharmacology/Toxicology
Potentially Inappropriate Medication List
Side effects
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Summary:Purpose The aim of this study was to measure the prevalence of potentially inappropriate medications (PIMs) by using the EU(7)-PIM list, STOPP (Screening Tool of Older Persons’ potentially inappropriate Prescriptions) version 2 criteria and the new comprehensive protocol. Methods This prospective study involved a sample of 276 consecutive elderly patients discharged from the university teaching hospital. Age, gender, diagnoses, medication history and medicines at discharge were recorded. The main outcome measure was the prevalence of PIMs according to each set of criteria: EU(7)-PIM list, STOPP version 2 criteria and comprehensive protocol. Results The median patient age (range) was 74 (65–92) years. The median number of prescribed medications was 7 (1–17). STOPP identified 393 PIMs affecting 190 patients (69%), EU(7)-PIM list identified 330 PIMs in 184 patients (66.7%) whilst the comprehensive protocol identified 134 PIMs in 102 patients (37%). STOPP version 2 criteria identified significantly more PIMs per patient than the other two protocols ( p  
ISSN:0031-6970
1432-1041
DOI:10.1007/s00228-017-2246-y