Nanocrystallization: A Unique Approach to Yield Bright Organic Nanocrystals for Biological Applications

A new bottom‐up nanocrystallization method is developed to fabricate highly fluorescent organic nanocrystals in aqueous media using an aggregation‐induced emission fluorogen (AIEgen) as an example. The nanocrystallization strategy leads to the fabrication of uniform nanocrystals of 110 ± 10 nm size...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2017-01, Vol.29 (1), p.np-n/a
Main Authors: Fateminia, S. M. Ali, Wang, Zhiming, Goh, Chi Ching, Manghnani, Purnima N., Wu, Wenbo, Mao, Duo, Ng, Lai Guan, Zhao, Zujin, Tang, Ben Zhong, Liu, Bin
Format: Article
Language:English
Subjects:
Agglomeration
aggregation‐induced emission
bioimaging
Brightness
Emission
Fluorescence
Materials science
Media
Nanocrystals
Nanoparticles
Nanostructure
organic nanoparticles
Strategy
stress‐induced crystallization
Water
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Summary:A new bottom‐up nanocrystallization method is developed to fabricate highly fluorescent organic nanocrystals in aqueous media using an aggregation‐induced emission fluorogen (AIEgen) as an example. The nanocrystallization strategy leads to the fabrication of uniform nanocrystals of 110 ± 10 nm size in aqueous media, which shows over 400% increase in brightness as compared to the amorphous nanoaggregates.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201604100