Coronary artery disease and hypertension in a non-selected spinal cord injury patient population

Retrospective observational comparative study. The objectives of this study were to assess the atherosclerosis diseases and risk factors prevalence after spinal cored injury (SCI). Loewenstein Rehabilitation Hospital, Israel. Data of 154 traumatic and non-traumatic SCI patients were retrospectively...

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Bibliographic Details
Published in:Spinal cord 2017-03, Vol.55 (3), p.321-326
Main Authors: Aidinoff, E, Bluvshtein, V, Bierman, U, Gelernter, I, Front, L, Catz, A
Format: Article
Language:English
Subjects:
Adult
Age Factors
Coronary Artery Disease - epidemiology
Coronary Artery Disease - etiology
Educational Status
Female
Follow-Up Studies
Humans
Hypertension - epidemiology
Hypertension - etiology
Israel - epidemiology
Male
Myocardial Infarction - epidemiology
Myocardial Infarction - etiology
Prevalence
Rehabilitation Centers
Retrospective Studies
Risk Factors
Severity of Illness Index
Sex Factors
Spinal Cord Injuries - complications
Spinal Cord Injuries - epidemiology
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Summary:Retrospective observational comparative study. The objectives of this study were to assess the atherosclerosis diseases and risk factors prevalence after spinal cored injury (SCI). Loewenstein Rehabilitation Hospital, Israel. Data of 154 traumatic and non-traumatic SCI patients were retrospectively collected. Coronary artery disease (CAD), myocardial infarction (MI), hypertension (HT) and risk factors for atherosclerotic diseases were examined after SCI for prevalence and effects, and compared with published corresponding data of the general population. CAD, MI and HT were found in 11.7, 6.7 and 29.2% of 120 patients, aged 53.4±11.1 years, 83.3% males, who survived until the end of the follow-up. Corresponding values for the general population, adjusted for age, gender and years of education, are 8.5, 6.6 and 24.9% in Israel, and 10.2% for CAD and 40.3% for HT, in US. Body mass index>30 increased the odds of acquiring CAD (P=0.016). Hypercholesterolemia and older age at injury increased the hazard for HT (P=0.044; P=0.019, respectively). A steady partner decreased the risk of CAD (P=0.029). HT was more prevalent at T -T than above T (52 vs 23.3%, P=0.02). Patients with SCI below T had a higher rate of diabetes mellitus, hypercholesterolemia, and past smoking, and fewer years of education than those with SCI above T (P=0.016; P=0.032; P=0.034; P=0.014, respectively). The prevalence of CAD, HT and some of their risk factors after SCI is generally, but not consistently and not statistically significant, slightly higher than in the corresponding general population. The challenge is to reduce the prevalence of atherosclerotic morbidity after SCI below that in the general population.
ISSN:1362-4393
1476-5624
DOI:10.1038/sc.2016.109