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IL-6 and TNF-α in unmedicated adults with ADHD: Relationship to cortisol awakening response

Highlights • The pro-inflammatory markers, IL-6 and TNF-α, do not appear to be primarily involved in adult ADHD. • There are ADHD subtype differences in the association between IL-6 and TNF-α, and cortisol awakening response. • The predominantly inattentive adults with ADHD showed negative correlati...

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Bibliographic Details
Published in:Psychoneuroendocrinology 2017-05, Vol.79, p.67-73
Main Authors: Corominas-Roso, M, Armario, A, Palomar, G, Corrales, M, Carrasco, J, Richarte, V, Ferrer, R, Casas, M, Ramos-Quiroga, J.A
Format: Article
Language:English
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Summary:Highlights • The pro-inflammatory markers, IL-6 and TNF-α, do not appear to be primarily involved in adult ADHD. • There are ADHD subtype differences in the association between IL-6 and TNF-α, and cortisol awakening response. • The predominantly inattentive adults with ADHD showed negative correlations between CAR and both IL-6 and TNF-α. • The inattentive and combined subtypes might have distinct neurobiological profiles regarding IL-6 and TNF-alpha and its association in basal cortisol.
ISSN:0306-4530
1873-3360
DOI:10.1016/j.psyneuen.2017.02.017