Arthritis during interferon beta-1b treatment in multiple sclerosis

Interferon beta (IFN-β) is the most widely prescribed disease-modifying drug for multiple sclerosis (MS). Therapy with IFN-βmay be associated with a number of adverse reactions. The development or exacerbation of other autoimmune diseases is a rare but reported side effect of IFN-βtherapy. In this c...

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Bibliographic Details
Published in:Multiple sclerosis 2002-12, Vol.8 (6), p.534-536
Main Authors: Altintas, A, Alici, Y, Melikoğlu, M, Siva, A
Format: Article
Language:English
Subjects:
Adjuvants, Immunologic - adverse effects
Adult
Antirheumatic Agents - administration & dosage
Arthritis - chemically induced
Arthritis - drug therapy
Biological and medical sciences
Female
Humans
Immunomodulators
Interferon beta-1b
Interferon-beta - adverse effects
Medical sciences
Methotrexate - administration & dosage
Multiple Sclerosis - drug therapy
Pharmacology. Drug treatments
Steroids - administration & dosage
Tropical medicine
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Summary:Interferon beta (IFN-β) is the most widely prescribed disease-modifying drug for multiple sclerosis (MS). Therapy with IFN-βmay be associated with a number of adverse reactions. The development or exacerbation of other autoimmune diseases is a rare but reported side effect of IFN-βtherapy. In this case report, we present clinical and laboratory findings of two MS patients who developed arthritis during IFN-β1b treatment, probably of autoimmune origin.
ISSN:1352-4585
1477-0970
DOI:10.1191/1352458502ms852xx