Liver involvement in Rendu-Osler disease: a case report and review of literature

A 48 years-old-woman was admitted for anectric cholestasis. A history of recurrent personal and familial epistaxis was noted. Biologic findings revealed iron deficiency anemia and moderate cholestasis. Viral serologic tests, antimitochondrie and anti smooth muscle antibodies were negative. Abdominal...

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Bibliographic Details
Published in:The Pan African medical journal 2016, Vol.24, p.326-326
Main Authors: Loukil, Hanen, Snoussi, Mouna, Fourati, Hela, Frikha, Faten, Salah, Raida Ben, Jallouli, Moez, Marzouk, Sameh, Mnif, Zeineb, Bahloul, Zouhir
Format: Article
Language:fre
Subjects:
Anemia, Iron-Deficiency - diagnosis
Anemia, Iron-Deficiency - drug therapy
Cholestasis, Intrahepatic - diagnosis
Cholestasis, Intrahepatic - pathology
Female
Humans
Iron - administration & dosage
Liver Diseases - diagnosis
Liver Diseases - diagnostic imaging
Liver Diseases - etiology
Middle Aged
Telangiectasia, Hereditary Hemorrhagic - complications
Telangiectasia, Hereditary Hemorrhagic - diagnosis
Telangiectasia, Hereditary Hemorrhagic - diagnostic imaging
Tomography, X-Ray Computed
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Summary:A 48 years-old-woman was admitted for anectric cholestasis. A history of recurrent personal and familial epistaxis was noted. Biologic findings revealed iron deficiency anemia and moderate cholestasis. Viral serologic tests, antimitochondrie and anti smooth muscle antibodies were negative. Abdominal tomography showed multiple arterio-venous shunts of the liver. The diagnosis of liver involvement due to Rendu Osler disease was made. Treatment with oral ferrous iron of 150 mg/day was administered and regular biological and morphologic controls of liver was decided.
ISSN:1937-8688
DOI:10.11604/pamj.2016.24.326.9816