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Thrombotic thrombocytopenic purpura in a new onset lupus patient?
We are presenting a case of TTP with undetectable levels of ADAMTS 13 in a 39-year-old woman. Diagnosis of systemic lupus was evoked in the setting of thrombotic microangiopathy. The patient presented normal renal function but important neurological impairment. Treatment with daily plasmapheresis as...
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| Published in: | Immunologic research 2017-04, Vol.65 (2), p.454-458 |
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| cites | cdi_FETCH-LOGICAL-c438t-72285e7ff4bb0a7729f25f5e9aba06a6e4cf248d0b58c7091fa92e2a9cc8d07a3 |
| container_end_page | 458 |
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| container_start_page | 454 |
| container_title | Immunologic research |
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| creator | González, Nery Sablón Lorenzo, Noel Parodis, Yanet Ortiz, Maria Belen Alonso Kechida, Melek Perez, Jose Carlos Rodriguez |
| description | We are presenting a case of TTP with undetectable levels of ADAMTS 13 in a 39-year-old woman. Diagnosis of systemic lupus was evoked in the setting of thrombotic microangiopathy. The patient presented normal renal function but important neurological impairment. Treatment with daily plasmapheresis as well as Rituximab, cyclophosphamide as steroids was required to achieve clinical improvement. |
| doi_str_mv | 10.1007/s12026-017-8898-y |
| format | article |
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Diagnosis of systemic lupus was evoked in the setting of thrombotic microangiopathy. The patient presented normal renal function but important neurological impairment. 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Diagnosis of systemic lupus was evoked in the setting of thrombotic microangiopathy. The patient presented normal renal function but important neurological impairment. Treatment with daily plasmapheresis as well as Rituximab, cyclophosphamide as steroids was required to achieve clinical improvement.</description><subject>2017</subject><subject>Adult</subject><subject>Allergology</subject><subject>Anemia, Hemolytic - diagnosis</subject><subject>Autoantibodies - blood</subject><subject>Autoimmune diseases</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Blood Platelets - immunology</subject><subject>Codeine - therapeutic use</subject><subject>Cyclophosphamide - therapeutic use</subject><subject>Female</subject><subject>Humans</subject><subject>Hydroxychloroquine - therapeutic use</subject><subject>Immunology</subject><subject>Internal Medicine</subject><subject>Lupus</subject><subject>Lupus Erythematosus, Systemic</subject><subject>Medicine/Public Health</subject><subject>Monoclonal antibodies</subject><subject>Novel Aspects in Lupus</subject><subject>Plasmapheresis</subject><subject>Purpura, Thrombotic Thrombocytopenic - diagnosis</subject><subject>Purpura, Thrombotic Thrombocytopenic - immunology</subject><subject>Remission Induction</subject><subject>Rituximab - therapeutic use</subject><subject>Sjogren's Syndrome - drug therapy</subject><subject>Systemic lupus erythematosus</subject><issn>0257-277X</issn><issn>1559-0755</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNp1kF1LwzAUhoMobk5_gDdS8MabapImTXIlY_gFA28meBfSLNGOrqlJivTfm9EpIgiBE855zpvwAHCO4DWCkN0EhCEuc4hYzrng-XAApohSkUNG6SGYQkxZjhl7nYCTEDYQopKQ4hhMMEcUIk6mYL56925buVjrLI5XPUTXmTY1ut6no7K6zVTWms_MtcHErOm7PmSdirVp4-0pOLKqCeZsX2fg5f5utXjMl88PT4v5Mtek4DFnGHNqmLWkqqBiDAuLqaVGqErBUpWGaIsJX8OKcs2gQFYJbLASWqcmU8UMXI25nXcfvQlRbuugTdOo1rg-SMRLSguCKEno5R9043rfpt8lSoiSCEZZotBIae9C8MbKztdb5QeJoNz5laNfmfzKnV85pJ2LfXJfbc36Z-NbaALwCIQ0at-M__X0v6lfhtiGWw</recordid><startdate>20170401</startdate><enddate>20170401</enddate><creator>González, Nery Sablón</creator><creator>Lorenzo, Noel</creator><creator>Parodis, Yanet</creator><creator>Ortiz, Maria Belen Alonso</creator><creator>Kechida, Melek</creator><creator>Perez, Jose Carlos Rodriguez</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T5</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20170401</creationdate><title>Thrombotic thrombocytopenic purpura in a new onset lupus patient?</title><author>González, Nery Sablón ; Lorenzo, Noel ; Parodis, Yanet ; Ortiz, Maria Belen Alonso ; Kechida, Melek ; Perez, Jose Carlos Rodriguez</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c438t-72285e7ff4bb0a7729f25f5e9aba06a6e4cf248d0b58c7091fa92e2a9cc8d07a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>2017</topic><topic>Adult</topic><topic>Allergology</topic><topic>Anemia, Hemolytic - diagnosis</topic><topic>Autoantibodies - blood</topic><topic>Autoimmune diseases</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Blood Platelets - immunology</topic><topic>Codeine - therapeutic use</topic><topic>Cyclophosphamide - therapeutic use</topic><topic>Female</topic><topic>Humans</topic><topic>Hydroxychloroquine - therapeutic use</topic><topic>Immunology</topic><topic>Internal Medicine</topic><topic>Lupus</topic><topic>Lupus Erythematosus, Systemic</topic><topic>Medicine/Public Health</topic><topic>Monoclonal antibodies</topic><topic>Novel Aspects in Lupus</topic><topic>Plasmapheresis</topic><topic>Purpura, Thrombotic Thrombocytopenic - diagnosis</topic><topic>Purpura, Thrombotic Thrombocytopenic - immunology</topic><topic>Remission Induction</topic><topic>Rituximab - therapeutic use</topic><topic>Sjogren's Syndrome - drug therapy</topic><topic>Systemic lupus erythematosus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>González, Nery Sablón</creatorcontrib><creatorcontrib>Lorenzo, Noel</creatorcontrib><creatorcontrib>Parodis, Yanet</creatorcontrib><creatorcontrib>Ortiz, Maria Belen Alonso</creatorcontrib><creatorcontrib>Kechida, Melek</creatorcontrib><creatorcontrib>Perez, Jose Carlos Rodriguez</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>ProQuest Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biological Sciences</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Immunologic research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>González, Nery Sablón</au><au>Lorenzo, Noel</au><au>Parodis, Yanet</au><au>Ortiz, Maria Belen Alonso</au><au>Kechida, Melek</au><au>Perez, Jose Carlos Rodriguez</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Thrombotic thrombocytopenic purpura in a new onset lupus patient?</atitle><jtitle>Immunologic research</jtitle><stitle>Immunol Res</stitle><addtitle>Immunol Res</addtitle><date>2017-04-01</date><risdate>2017</risdate><volume>65</volume><issue>2</issue><spage>454</spage><epage>458</epage><pages>454-458</pages><issn>0257-277X</issn><eissn>1559-0755</eissn><notes>ObjectType-Case Study-2</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-4</notes><notes>content type line 23</notes><notes>ObjectType-Report-1</notes><notes>ObjectType-Article-3</notes><abstract>We are presenting a case of TTP with undetectable levels of ADAMTS 13 in a 39-year-old woman. Diagnosis of systemic lupus was evoked in the setting of thrombotic microangiopathy. The patient presented normal renal function but important neurological impairment. Treatment with daily plasmapheresis as well as Rituximab, cyclophosphamide as steroids was required to achieve clinical improvement.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>28150184</pmid><doi>10.1007/s12026-017-8898-y</doi><tpages>5</tpages></addata></record> |
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| subjects | 2017 Adult Allergology Anemia, Hemolytic - diagnosis Autoantibodies - blood Autoimmune diseases Biomedical and Life Sciences Biomedicine Blood Platelets - immunology Codeine - therapeutic use Cyclophosphamide - therapeutic use Female Humans Hydroxychloroquine - therapeutic use Immunology Internal Medicine Lupus Lupus Erythematosus, Systemic Medicine/Public Health Monoclonal antibodies Novel Aspects in Lupus Plasmapheresis Purpura, Thrombotic Thrombocytopenic - diagnosis Purpura, Thrombotic Thrombocytopenic - immunology Remission Induction Rituximab - therapeutic use Sjogren's Syndrome - drug therapy Systemic lupus erythematosus |
| title | Thrombotic thrombocytopenic purpura in a new onset lupus patient? |
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