Case of pleomorphic rhabdomyosarcoma arising on subcutaneous tissue in an adult patient: Review of the published works of 13 cases arising on cutaneous or subcutaneous tissue

Rhabdomyosarcoma (RMS) is a malignant mesenchymal tumor usually occurring in children, young adults, and predominantly arising in the head and neck or deep soft tissue of the extremities. Pleomorphic RMS (PRMS) arising on subcutaneous tissue in an adult patient's trunk is extremely rare. We pre...

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Bibliographic Details
Published in:Journal of dermatology 2017-01, Vol.44 (1), p.59-63
Main Authors: Watanabe, Mai, Ansai, Shin‐ichi, Iwakiri, Itaru, Fukumoto, Takaya, Murakami, Masahiro
Format: Article
Language:English
Subjects:
adult
Antineoplastic Agents - administration & dosage
Antineoplastic Agents - therapeutic use
Antineoplastic Combined Chemotherapy Protocols
Axilla
Back
Biopsy
Chemotherapy, Adjuvant
Cyclophosphamide - administration & dosage
Cyclophosphamide - therapeutic use
Dactinomycin - administration & dosage
Dactinomycin - therapeutic use
dermis
Humans
Immunohistochemistry
Lymph Nodes
Lymphatic Metastasis
Male
Middle Aged
Neoplasm Recurrence, Local - drug therapy
pleomorphic
Rare Diseases - diagnosis
Rare Diseases - pathology
Rare Diseases - surgery
rhabdomyosarcoma
Rhabdomyosarcoma - diagnosis
Rhabdomyosarcoma - drug therapy
Rhabdomyosarcoma - pathology
Rhabdomyosarcoma - surgery
Soft Tissue Neoplasms - diagnosis
Soft Tissue Neoplasms - pathology
Soft Tissue Neoplasms - surgery
Subcutaneous Tissue - pathology
subcutis
Tomography, X-Ray Computed
Vincristine - administration & dosage
Vincristine - therapeutic use
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Summary:Rhabdomyosarcoma (RMS) is a malignant mesenchymal tumor usually occurring in children, young adults, and predominantly arising in the head and neck or deep soft tissue of the extremities. Pleomorphic RMS (PRMS) arising on subcutaneous tissue in an adult patient's trunk is extremely rare. We present a case of primary PRMS occurring on the back of a 50‐year‐old man. The tumor was diagnosed by histological and immunohistochemical findings of the resected specimen. One month after the surgery, axillary lymph node metastases were found. Subsequently, the patient received three cycles of combined chemotherapy. The rest of those axillary lymph nodes were reduced in size and there was no local recurrence 6 months postoperatively. PRMS is a very rare but aggressive tumor. Thus, it is important to confirm the diagnosis and provide adequate treatments.
ISSN:0385-2407
1346-8138
DOI:10.1111/1346-8138.13549