Rapid diagnosis of adenovirus respiratory tract infections by immunochromatography

A one-step diagnostic test based on an immunochromatographic (IC) assay for adenovirus was evaluated with purified adenovirus and clinical specimens. According to five clinically common serotypes of purified adenovirus tested, the IC test was more sensitive than two commercially available enzyme imm...

Full description

Saved in:
Bibliographic Details
Published in:Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 1999-12, Vol.5 (4), p.220-222
Main Authors: Ouchi, Kazunobu, Hasegawa, Keiko, Nonaka, Yukiko, Matsushima, Hiroshi, Komura, Hayashi, Maki, Takashi, Nakazawa, Teruko
Format: Article
Language:English
Subjects:
Adenovirus
Immunochromatography
Rapid diagnosis
Respiratory tract infection
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A one-step diagnostic test based on an immunochromatographic (IC) assay for adenovirus was evaluated with purified adenovirus and clinical specimens. According to five clinically common serotypes of purified adenovirus tested, the IC test was more sensitive than two commercially available enzyme immunoassay (EIA) test kits. For tonsilopharyngeal specimens from 63 febrile pediatric patients with suspected adenoviral upper respiratory tract infection, the sensitivity and specificity of the IC test against viral isolation by cell culture was 88.5% (23/26) and 100% (37/37), respectively. The IC test, which is quicker and easier to perform than EIA test kits, is very useful in the rapid diagnosis of adenoviral upper respiratory tract infection of pediatric patients.
ISSN:1341-321X
1437-7780
DOI:10.1007/s101560050040