A New Bromopyrrole Alkaloid and the Optical Resolution of the Racemate from the Marine Sponge Homaxinella sp

A new bromopyrrole alkaloid (1) along with (±)-2 and (±)-longamide (3) has been isolated from the Japanese marine sponge Homaxinella sp. The structures of the compounds were proposed on the basis of spectroscopic data. The optical resolution of (±)-2 by chiral HPLC was successful and afforded the tw...

Full description

Saved in:
Bibliographic Details
Published in:Journal of natural products (Washington, D.C.) D.C.), 1998-11, Vol.61 (11), p.1433-1434
Main Authors: Umeyama, Akemi, Ito, Seiichi, Yuasa, Eri, Arihara, Shigenobu, Yamada, Takeshi
Format: Article
Language:English
Subjects:
Biological and medical sciences
bromine
chemical composition
chemical structure
derivatives
enantiomers
General pharmacology
Homaxinella
longamide
Marine
Medical sciences
parazoa
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
pyrrolidine alkaloids
spectral analysis
sponges
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A new bromopyrrole alkaloid (1) along with (±)-2 and (±)-longamide (3) has been isolated from the Japanese marine sponge Homaxinella sp. The structures of the compounds were proposed on the basis of spectroscopic data. The optical resolution of (±)-2 by chiral HPLC was successful and afforded the two enantiomers, (+)-2 and (−)-2.
ISSN:0163-3864
1520-6025
DOI:10.1021/np980207u