Pathologic Risk Factors for Metastatic Disease in Postpubertal Patients With Clinical Stage I Testicular Stromal Tumors

Objective To systematically review the existing literature to analyze the impact of previously identified pathologic risk factors on harboring occult metastatic disease (OMD) in patients with Clinical Stage I testicular stromal tumors (TSTs). Materials and Methods A literature search using PubMed wa...

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Bibliographic Details
Published in:Urology (Ridgewood, N.J.) N.J.), 2016-11, Vol.97, p.138-144
Main Authors: Rove, Kyle O, Maroni, Paul D, Cost, Carrye R, Fairclough, Diane L, Giannarini, Gianluca, Harris, Anne K, Schultz, Kris Ann P, Cost, Nicholas G
Format: Article
Language:English
Subjects:
Urology
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Summary:Objective To systematically review the existing literature to analyze the impact of previously identified pathologic risk factors on harboring occult metastatic disease (OMD) in patients with Clinical Stage I testicular stromal tumors (TSTs). Materials and Methods A literature search using PubMed was conducted using the following terms: “testicular stromal tumors,” “testicular Leydig cell tumors,” “testicular Sertoli tumors,” “testicular interstitial tumors,” “testicular granulosa tumor,” and “testicular sex cord tumors.” For analysis, we included only studies with data on available recurrence, survival, and time-to-event. We hypothesized that patients with ≥2 risk factors would experience lower 5-year OMD-free survival (OMDFS) than those with
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2016.06.066