Fatty acid status and antioxidant defence system in mothers and their newborns after salmon intake during late pregnancy

Abstract Objective The aim of the present study was to assess the maternal and newborn status of erythrocyte fatty acids and the antioxidant defence system after the intake of two portions of salmon per week during late pregnancy. Research Methods and Procedures Pregnant women ( n =123) were randoml...

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Bibliographic Details
Published in:Nutrition (Burbank, Los Angeles County, Calif.) Los Angeles County, Calif.), 2017-01, Vol.33, p.157-162
Main Authors: Garcia-Rodriguez, Cruz E, Olza, Josune, Mesa, Maria D, Aguilera, Concepcion M, Miles, Elizabeth A, Noakes, Paul S, Vlachava, Maria, Kremmyda, Lefkothea-Stella, Diaper, Norma D, Godfrey, Keith M, Calder, Philip C, Gil, Angel
Format: Article
Language:English
Subjects:
Adult
Animals
Antioxidants
Antioxidants - analysis
Diet
England
Erythrocytes - metabolism
Fatty acids
Fatty Acids - blood
Fatty Acids - metabolism
Female
Fetal Blood - chemistry
Fetal Blood - cytology
Fish oils
Gastroenterology and Hepatology
Glutathione - blood
Glutathione Peroxidase - blood
Humans
Infant, Newborn
Male
Maternal Nutritional Physiological Phenomena
Newborn
Nutritional Status
Oxidative Stress
Plasma
Pregnancy
Pregnancy Trimester, Second
Pregnancy Trimester, Third
Rodents
Salmon
Salmonidae
Seafood
Selenium - blood
Studies
ω-3
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Summary:Abstract Objective The aim of the present study was to assess the maternal and newborn status of erythrocyte fatty acids and the antioxidant defence system after the intake of two portions of salmon per week during late pregnancy. Research Methods and Procedures Pregnant women ( n =123) were randomly assigned to continue their habitual diet which was low in oily fish (control group, n =61) or to consume two 150-g salmon portions per week (salmon group, n = 62) from 20 week of gestation until delivery. Fatty acids, selenium and glutathione concentrations and antioxidant defence enzyme activities were measured in maternal erythrocytes at 20, 34 and 38 weeks of pregnancy, and in cord erythrocytes collected at birth. Plasma concentrations of antioxidant molecules were also measured. Results Compared with the control group, consuming salmon had little effect on erythrocyte fatty acids in either mothers or newborns. Components of the antioxidant defence system did not differ between groups. Glutathione peroxidase activity and the concentrations of tocopherols, retinol and coenzyme Q10 were significantly lower in cord blood compared to maternal blood at week 38 in both groups. Conclusion Maternal and newborn erythrocyte fatty acids are little affected by the intake of two portions of salmon per week during the second half of pregnancy, although erythrocyte DHA might be increased in newborns. Maternal and newborn antioxidant defence systems are not impaired by intake of salmon from 20 weeks gestation.
ISSN:0899-9007
1873-1244
DOI:10.1016/j.nut.2016.05.015