Dimensions of Schizophrenia and their time course of response to a second generation antipsychotic olanzapine- a clinical study

Highlights • Symptoms and signs of schizophrenia are myriad. • Several attempts have been made to group symptoms of schizophrenia into meaningful dimensions. • Differential time course of symptom dimensions response to olanzapine in drug naïve first episode schizophrenia were examined. • Olanzapine...

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Bibliographic Details
Published in:Asian journal of psychiatry 2016-12, Vol.24, p.17-22
Main Authors: Birur, Badari, MD, Thirthalli, Jagadisha, MD, Janakiramaiah, N., MD, Shelton, Richard C., MD, Gangadhar, Bangalore N., MD
Format: Article
Language:English
Subjects:
Adolescent
Adult
Antipsychotic Agents - administration & dosage
Antipsychotic Agents - pharmacology
Benzodiazepines - administration & dosage
Benzodiazepines - pharmacology
Dimensions
Drug naïve
Female
First episode schizophrenia
Humans
Internal Medicine
Male
Middle Aged
Outcome Assessment (Health Care)
Psychiatry
Schizophrenia - drug therapy
Schizophrenia - physiopathology
Second generation antipsychotic olanzapine
Time Factors
Young Adult
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Description
Summary:Highlights • Symptoms and signs of schizophrenia are myriad. • Several attempts have been made to group symptoms of schizophrenia into meaningful dimensions. • Differential time course of symptom dimensions response to olanzapine in drug naïve first episode schizophrenia were examined. • Olanzapine produced reduction in all symptom dimensions of schizophrenia.
ISSN:1876-2018
1876-2026
DOI:10.1016/j.ajp.2016.08.007