Early esophageal cancer screening in China

Abstract In China, the incidence of esophageal cancer (EC) and its related mortality are high. Screening strategies aiming at early diagnosis can improve the prognosis. Researches on detection of early EC, especially in China are reviewed. Compared to esophageal balloon cytology or routine endoscopy...

Full description

Saved in:
Bibliographic Details
Published in:Baillière's best practice & research. Clinical gastroenterology 2015-12, Vol.29 (6), p.885-893
Main Authors: Gao, Qin-Yan, M.D., Ph.D, Fang, Jing-Yuan, M.D., Ph.D
Format: Article
Language:English
Subjects:
Biopsy
Cellular biology
China
Clinical medicine
Cost-Benefit Analysis
Diagnostic Imaging - methods
Early Detection of Cancer - methods
Endoscopy
Esophageal cancer
Esophageal Neoplasms - pathology
Esophagoscopy - methods
Gastroenterology and Hepatology
Humans
Iodine
Medical prognosis
Mortality
Population
Screening
Studies
Urban areas
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract In China, the incidence of esophageal cancer (EC) and its related mortality are high. Screening strategies aiming at early diagnosis can improve the prognosis. Researches on detection of early EC, especially in China are reviewed. Compared to esophageal balloon cytology or routine endoscopy, chromoendoscopy with Lugol's staining and biopsy appears to be the gold standard for early EC diagnosis in China today. Narrow-band imaging endoscopy, Confocal Laser endomicroscopy and other novel diagnostic approaches are more and more widely used in developed urban areas, but cost and lack of essential training to the endoscopists have made their use limited in rural areas. No specific biomarkers or serum markers were strongly commended to be used in screening strategies currently, which need to be evaluated in future. Trials on organized screening have been proposed in some regions of china with high disease prevalence. Screening in these areas has been shown to be cost effective.
ISSN:1521-6918
1532-1916
DOI:10.1016/j.bpg.2015.09.018