The effects of sevoflurane and desflurane on the hemodynamics and respiratory functions in laparoscopic sleeve gastrectomy

Abstract Study objectives Sleeve gastrectomy has been one of the most commonly performed bariatric surgery methods. The study aimed to compare the effects of 2 most commonly used inhalation anesthetics, sevoflurane and desflurane, on the peroperative hemodynamic alterations and postoperative respira...

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Bibliographic Details
Published in:Journal of clinical anesthesia 2016-12, Vol.35, p.441-445
Main Authors: Ozdogan, Hatice Kaya, MD, Cetinkunar, Suleyman, MD, Karateke, Faruk, MD, Cetinalp, Sibel, MD, Celik, Muge, MD, Ozyazici, Sefa, MD
Format: Article
Language:English
Subjects:
Adult
Anesthesia
Anesthesia & Perioperative Care
Anesthetics, Inhalation - pharmacology
Blood pressure
Body mass index
Circulatory system
Cohort Studies
Desflurane
Drugs
Female
Gastrectomy
Hemodynamics
Hemodynamics - drug effects
Humans
Intubation
Isoflurane - analogs & derivatives
Isoflurane - pharmacology
Laparoscopy
Male
Methyl Ethers - pharmacology
Morbid obesity
Obesity
Obesity, Morbid - surgery
Pain Medicine
Prospective Studies
Respiration - drug effects
Respiratory Function Tests
Sevoflurane
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Summary:Abstract Study objectives Sleeve gastrectomy has been one of the most commonly performed bariatric surgery methods. The study aimed to compare the effects of 2 most commonly used inhalation anesthetics, sevoflurane and desflurane, on the peroperative hemodynamic alterations and postoperative respiratory functions in morbidly obese patients undergoing sleeve gastrectomy. Design Nonrandomized cohort. Settings Operating room, postoperative period. Patients Eighty-four morbidly obese patients with a body mass index greater than 40 kg/m2 who had scheduled to undergo sleeve gastrectomy operation were prospectively included in the study. Interventions Patients were divided into 2 groups. The maintenance of inhalation anesthesia was performed by sevoflurane in 1 group (sevoflurane group) and desflurane (desflurane group) in the other group. Measurements Demographic features, peroperative hemodynamic alterations, and the results of preoperative and postoperative 24th hour respiratory function tests were recorded. Results There was not any statistically significant difference between groups regarding age, sex, body mass index, anesthesia time, peroperative mean arterial pressure, arterial oxygen saturation, end-tidal carbon dioxide, and preoperative or postoperative forced expiratory volume 1/forced vital capacity ratios. Conclusion We determined that both desflurane and sevoflurane provide similar intraoperative hemodynamic and early postoperative respiratory functions in morbidly obese patients in laparoscopic sleeve gastrectomy. Both agents can be regarded as alternatives for inhalation anesthetics in maintenance of anesthesia.
ISSN:0952-8180
1873-4529
DOI:10.1016/j.jclinane.2016.08.028